Magnetic Solid-Phase Extraction Based on C18 Nanoparticles for the Determination of Pesticides in Aquaculture Water Samples

In this study, C18-functionalized magnetic silica nanoparticles (Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>@C18) were used as adsorbents for the magnetic solid-phase extraction (MSPE) of organic contaminants commonly applied to aquaculture water (organic booster...

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Main Authors: Margarita Kapsi, Vasileios Sakkas, Vasiliki Boti, Triantafyllos Albanis
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/30/9/2076
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author Margarita Kapsi
Vasileios Sakkas
Vasiliki Boti
Triantafyllos Albanis
author_facet Margarita Kapsi
Vasileios Sakkas
Vasiliki Boti
Triantafyllos Albanis
author_sort Margarita Kapsi
collection DOAJ
description In this study, C18-functionalized magnetic silica nanoparticles (Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>@C18) were used as adsorbents for the magnetic solid-phase extraction (MSPE) of organic contaminants commonly applied to aquaculture water (organic booster biocides, herbicides, and insecticides) followed by Gas Chromatography coupled to Mass Spectrometry (GC–MS). The extraction conditions and efficiency of the nanoparticles for the determination of ten pesticides (atrazine, ethoxyquine, chlorothalonil, chlorpyriphos methyl, methyl parathion, chlorpyriphos, resmethrin, λ-cyhalothrin, permethrin, and irgarol) were thoroughly investigated. Several experimental parameters affecting the extraction efficiency such as the amount of sorbent, extraction time, and elution time were optimized by employing experimental designs as response surface methodology. Validation experiments showed that the average recoveries of target analytes were in the range of 60% to 99%. The optimized method exhibited good linearity (R<sup>2</sup> > 0.9901) and satisfactory precision (Relative Standard deviations, RSDs < 15%). The method detection limits ranged between 1.9 ng L<sup>−1</sup> and 62 ng L<sup>−1</sup>. Finally, the MSPE method was successfully applied to aquaculture water samples collected from the Thesprotia region (N.W. Greece), Thermaikos Gulf (N. Greece) and Butrint (S.W. Albania).
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spelling doaj-art-9c45b6ffdc734da58e793b7a4438ad3f2025-08-20T02:59:08ZengMDPI AGMolecules1420-30492025-05-01309207610.3390/molecules30092076Magnetic Solid-Phase Extraction Based on C18 Nanoparticles for the Determination of Pesticides in Aquaculture Water SamplesMargarita Kapsi0Vasileios Sakkas1Vasiliki Boti2Triantafyllos Albanis3Laboratory of Industrial Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, GreeceLaboratory of Analytical Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, GreeceLaboratory of Industrial Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, GreeceLaboratory of Industrial Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, GreeceIn this study, C18-functionalized magnetic silica nanoparticles (Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>@C18) were used as adsorbents for the magnetic solid-phase extraction (MSPE) of organic contaminants commonly applied to aquaculture water (organic booster biocides, herbicides, and insecticides) followed by Gas Chromatography coupled to Mass Spectrometry (GC–MS). The extraction conditions and efficiency of the nanoparticles for the determination of ten pesticides (atrazine, ethoxyquine, chlorothalonil, chlorpyriphos methyl, methyl parathion, chlorpyriphos, resmethrin, λ-cyhalothrin, permethrin, and irgarol) were thoroughly investigated. Several experimental parameters affecting the extraction efficiency such as the amount of sorbent, extraction time, and elution time were optimized by employing experimental designs as response surface methodology. Validation experiments showed that the average recoveries of target analytes were in the range of 60% to 99%. The optimized method exhibited good linearity (R<sup>2</sup> > 0.9901) and satisfactory precision (Relative Standard deviations, RSDs < 15%). The method detection limits ranged between 1.9 ng L<sup>−1</sup> and 62 ng L<sup>−1</sup>. Finally, the MSPE method was successfully applied to aquaculture water samples collected from the Thesprotia region (N.W. Greece), Thermaikos Gulf (N. Greece) and Butrint (S.W. Albania).https://www.mdpi.com/1420-3049/30/9/2076chemometric toolsexperimental designmagnetic octadecylsilane nanoparticlespesticidesaquaculture waters
spellingShingle Margarita Kapsi
Vasileios Sakkas
Vasiliki Boti
Triantafyllos Albanis
Magnetic Solid-Phase Extraction Based on C18 Nanoparticles for the Determination of Pesticides in Aquaculture Water Samples
Molecules
chemometric tools
experimental design
magnetic octadecylsilane nanoparticles
pesticides
aquaculture waters
title Magnetic Solid-Phase Extraction Based on C18 Nanoparticles for the Determination of Pesticides in Aquaculture Water Samples
title_full Magnetic Solid-Phase Extraction Based on C18 Nanoparticles for the Determination of Pesticides in Aquaculture Water Samples
title_fullStr Magnetic Solid-Phase Extraction Based on C18 Nanoparticles for the Determination of Pesticides in Aquaculture Water Samples
title_full_unstemmed Magnetic Solid-Phase Extraction Based on C18 Nanoparticles for the Determination of Pesticides in Aquaculture Water Samples
title_short Magnetic Solid-Phase Extraction Based on C18 Nanoparticles for the Determination of Pesticides in Aquaculture Water Samples
title_sort magnetic solid phase extraction based on c18 nanoparticles for the determination of pesticides in aquaculture water samples
topic chemometric tools
experimental design
magnetic octadecylsilane nanoparticles
pesticides
aquaculture waters
url https://www.mdpi.com/1420-3049/30/9/2076
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AT vasilikiboti magneticsolidphaseextractionbasedonc18nanoparticlesforthedeterminationofpesticidesinaquaculturewatersamples
AT triantafyllosalbanis magneticsolidphaseextractionbasedonc18nanoparticlesforthedeterminationofpesticidesinaquaculturewatersamples