Multiple Myeloma Case Developed During the Use of the Teriparatide
Recombinant human parathyroid hormone (1-34) (rhPTH 1-34), teriparatide, is a class of anabolic therapy for treating severe osteoporosis. Although plasma cell dyscrasias are excluded among the known side effects of teriparatide treatment, their association in the form of case reports has been report...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2022-04-01
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| Series: | Türk Osteoporoz Dergisi |
| Subjects: | |
| Online Access: |
http://www.turkosteoporozdergisi.org/archives/archive-detail/article-preview/multiple-myeloma-case-developed-during-the-use-of-/51345
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| _version_ | 1849399250017845248 |
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| author | Zehra Erdemir Ayşe İyiyapıcı Ünübol Mustafa Ünübol Esra Ercan Aktekin İrfan Yavaşoğlu Engin Güney |
| author_facet | Zehra Erdemir Ayşe İyiyapıcı Ünübol Mustafa Ünübol Esra Ercan Aktekin İrfan Yavaşoğlu Engin Güney |
| author_sort | Zehra Erdemir |
| collection | DOAJ |
| description | Recombinant human parathyroid hormone (1-34) (rhPTH 1-34), teriparatide, is a class of anabolic therapy for treating severe osteoporosis. Although plasma cell dyscrasias are excluded among the known side effects of teriparatide treatment, their association in the form of case reports has been reported. PTH 1-34 stimulates osteoblasts and indirectly stimulates receptor activator of nuclear factor kappa-B ligand (RANKL), RANK and IL-6 with osteoclast stimulation. There are relationships between RANKL/OPG system and osteoclast and osteoblast activity in multiple myeloma. We report a case with multiple myeloma who developed malignant myeloma after teriparatide treatment. |
| format | Article |
| id | doaj-art-9c459f4f61b042608bb08c47ccd28a3b |
| institution | Kabale University |
| issn | 2147-2653 |
| language | English |
| publishDate | 2022-04-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Türk Osteoporoz Dergisi |
| spelling | doaj-art-9c459f4f61b042608bb08c47ccd28a3b2025-08-20T03:38:23ZengGalenos Publishing HouseTürk Osteoporoz Dergisi2147-26532022-04-01281697310.4274/tod.galenos.2021.2458213049054Multiple Myeloma Case Developed During the Use of the TeriparatideZehra Erdemir0Ayşe İyiyapıcı Ünübol1Mustafa Ünübol2Esra Ercan Aktekin3İrfan Yavaşoğlu4Engin Güney5 Aydın Adnan Menderes Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Endokrinoloji ve Metabolizma Hastalıkları Bilim Dalı, Aydın, Türkiye Aydın Atatürk Devlet Hastanesi, Fizik Tedavi ve Rehabilitasyon Kliniği, Aydın, Türkiye Aydın Adnan Menderes Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Endokrinoloji ve Metabolizma Hastalıkları Bilim Dalı, Aydın, Türkiye Aydın Adnan Menderes Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Aydın, Türkiye Aydın Adnan Menderes Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Hematoloji Bilim Dalı, Aydın, Türkiye Aydın Adnan Menderes Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Endokrinoloji ve Metabolizma Hastalıkları Bilim Dalı, Aydın, Türkiye Recombinant human parathyroid hormone (1-34) (rhPTH 1-34), teriparatide, is a class of anabolic therapy for treating severe osteoporosis. Although plasma cell dyscrasias are excluded among the known side effects of teriparatide treatment, their association in the form of case reports has been reported. PTH 1-34 stimulates osteoblasts and indirectly stimulates receptor activator of nuclear factor kappa-B ligand (RANKL), RANK and IL-6 with osteoclast stimulation. There are relationships between RANKL/OPG system and osteoclast and osteoblast activity in multiple myeloma. We report a case with multiple myeloma who developed malignant myeloma after teriparatide treatment. http://www.turkosteoporozdergisi.org/archives/archive-detail/article-preview/multiple-myeloma-case-developed-during-the-use-of-/51345 osteoporosisteriparatidemultiple myeloma |
| spellingShingle | Zehra Erdemir Ayşe İyiyapıcı Ünübol Mustafa Ünübol Esra Ercan Aktekin İrfan Yavaşoğlu Engin Güney Multiple Myeloma Case Developed During the Use of the Teriparatide Türk Osteoporoz Dergisi osteoporosis teriparatide multiple myeloma |
| title | Multiple Myeloma Case Developed During the Use of the Teriparatide |
| title_full | Multiple Myeloma Case Developed During the Use of the Teriparatide |
| title_fullStr | Multiple Myeloma Case Developed During the Use of the Teriparatide |
| title_full_unstemmed | Multiple Myeloma Case Developed During the Use of the Teriparatide |
| title_short | Multiple Myeloma Case Developed During the Use of the Teriparatide |
| title_sort | multiple myeloma case developed during the use of the teriparatide |
| topic | osteoporosis teriparatide multiple myeloma |
| url |
http://www.turkosteoporozdergisi.org/archives/archive-detail/article-preview/multiple-myeloma-case-developed-during-the-use-of-/51345
|
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