Insulin resistance in pathogenesis of type 2 diabetes mellitus

Insulin resistance in pathogenesis of type 2 diabetes mellitus

This review focuses on the mechanisms of impaired sensitivity to insulin associated withevolution of carbohydrate metabolism disorders from enhanced fasting glycemia (EFG) to impaired glucose tolerance (IGT) and type 2 diabetes.Disturbances of glucose utilization at the receptor and post-receptor le...

Full description

Saved in:

Bibliographic Details
Main Author:	Alexander Yur'evich Mayorov
Format:	Article
Language:	English
Published:	Endocrinology Research Centre 2011-03-01
Series:	Сахарный диабет
Subjects:	insulin resistance type 2 diabetes mellitus glucose utilization in tissues m-index disturbed fasting glycemia impaired glucose tolerance
Online Access:	https://www.dia-endojournals.ru/jour/article/view/6248
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Metabolites Link Intake of a Healthy Diet to Better Insulin and Glucose Homeostasis in the Microbiome and Insulin Longitudinal Evaluation Study (MILES)
by: Alexis C Wood, et al.
Published: (2024-11-01)

Comparative assessment of modern parameters of glycemic control in children with type 1 diabetes after switching to fast-acting insulin aspart using Flash Glucose Monitoring in real clinical practice
by: Y. V. Girsh, et al.
Published: (2022-12-01)

Prevalence of type 2 diabetes mellitus and other abnormalities of carbohydrate metabolism depending on diagnostic criteria
by: Alexander Vasil'evich Dreval', et al.
Published: (2010-03-01)

Resolution on the results of the first working meeting of the scientific advisory board «Actual problems of glycemic variability as a new criterion of glycemic control and safety of diabetes therapy»
by: Mikhail B. Antsiferov, et al.
Published: (2019-08-01)

Disse index and free fatty acids as markers of insulin resistance and their association with hospital outcomes of coronary bypass surgery in patients with different glycemic status
by: N. A. Bezdenezhnykh, et al.
Published: (2023-02-01)

Association of gestational diabetes mellitus diagnosed at different time points in oral glucose tolerance test with adverse pregnancy outcomes: a retrospective cohort study
by: Ruipeng Lin, et al.
Published: (2025-05-01)

Clinical and psychological aspects of hypoglycemia in patients with diabetes mellitus
by: Olga Georgievna Mel'nikova, et al.
Published: (2010-09-01)

Glycemic trends and reduced insulin requirements in adolescents with type 1 diabetes during a therapeutic recreational camp: Insights from continuous glucose monitoring
by: Varga Boglárka, et al.
Published: (2025-07-01)

Beneficial Role of Increased Glucose Infusion in Decompensated Type 2 Diabetes Patient
by: Marie Ticha, et al.
Published: (2025-06-01)

Practicalities of Flash-monitoring systems utilization in the questionnaire survey of children and adolescents with type 1 diabetes mellitus
by: A. M. Rimskaya, et al.
Published: (2023-02-01)

Effect of meal time on postprandial glycemia in patients with type 2 diabetes mellitus and obesity not receiving insulin
by: I. V. Misnikova, et al.
Published: (2023-11-01)

Age-specific abnormal glucose metabolism in HIV-positive people on antiviral therapy in China: a multicenter case-control study
by: Lijun Xu, et al.
Published: (2025-12-01)

GLYCEMIA CONTROL, INSULIN RESISTANCE, AND FUNCTIONAL ACTIVITY OF T-HELPER SUBPOPULATIONS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS
by: I. V. Kologrivova, et al.
Published: (2014-03-01)

Systems of continuous subcutaneous insulin infusion to maintain metabolic compensation for type 1 diabetes mellitus among children and adolescents
by: Elena B. Bashnina, et al.
Published: (2019-12-01)

The effects of structured self-monitoring of blood glucose on therapeutic effectiveness and adherence in patients with type 2 diabetes mellitus initiating insulin treatment
by: Lyudmila Alexandrovna Suvorova, et al.
Published: (2013-12-01)

Leptin secretion and severity of glycemic disorders in women with body weight excess
by: Alexander Vasil'evich Dreval', et al.
Published: (2013-06-01)

Multiple positive points during the 75 g oral glucose tolerance test are good predictors for early insulin therapy in gestational diabetes mellitus diagnosed before 24 gestational weeks
by: Yoshifumi Kasuga, et al.
Published: (2024-12-01)

Overcoming marked insulin resistance in a patient with type 2 diabetes mellitus by means of insulin pumptherapy
by: Ekaterina Viktorovna Artemova, et al.
Published: (2012-09-01)

Contributions of Hepatic Insulin Resistance and Islet β-Cell Dysfunction to the Blood Glucose Spectrum in Newly Diagnosed Type 2 Diabetes Mellitus
by: Mengge Yang, et al.
Published: (2025-07-01)

Topical problems of diabetes treatment during pregnancy
by: Irina Yur'evna Demidova, et al.
Published: (2009-12-01)

Prevalence of Gestational Diabetes Mellitus in Pregnant Women Referring to Gynecology and Obstetrics Clinics
by: Hajieh BiBi Shahbazian, et al.
Published: (2012-05-01)

Levels of anti-insulin antibodies in diabetic retinopathy patients: an observational cross-sectional study
by: Bismark N Mohammed, et al.
Published: (2024-12-01)

A new classification method for gestational diabetes mellitus: a study on the relationship between abnormal blood glucose values at different time points in oral glucose tolerance test and adverse maternal and neonatal outcomes in pregnant women with gestational diabetes mellitusAJOG Global Reports at a Glance
by: Yongqing Zhang, MD, et al.
Published: (2024-11-01)

Prescribing insulin in type 1 diabetes mellitus: an update for general practitioners
by: J.A. Dave, et al.
Published: (2007-12-01)

Predicting isolated impaired glucose tolerance without oral glucose tolerance test using machine learning in Chinese Han men
by: Lin Wang, et al.
Published: (2025-04-01)

Modern Aspects of the Clinic, Diagnosis and Treatment of Prediabetes
by: N. V. Pyrikova, et al.
Published: (2020-10-01)

Hypoglycemia in type 2 diabetes patients treated with insulin: the advantages of continuous glucose monitoring
by: Vadim Valer'evich Klimontov, et al.
Published: (2014-03-01)

The death rate of patients with type 2 diabetes mellitus and impaired glucose tolerance from cardiovascular disease
by: E. A. Palferova
Published: (2005-04-01)

THE INFLUENCE OF GROWTH HORMONE TREATMENT ON INSULIN SENSITIVITY IN CHILDREN AND ADOLESCENTS
by: Aslı Derya Kardelen Al, et al.
Published: (2023-10-01)

Hyperglycemia Is a Potential Prognostic Factor for Exacerbation in Severe Psoriasis with Diabetes or Prediabetes
by: Yongpisarn T, et al.
Published: (2025-02-01)

Glycemia Risk Index: A New Metric to Rule Them All?
by: Gonzalo Diaz Soto, et al.
Published: (2025-06-01)

КОРРЕКЦИЯ УГЛЕВОДНОГО ОБМЕНА У БОЛЬНЫХ С МЕТАБОЛИЧЕСКИМ СИНДРОМОМ ПО ДАНЫМ СУТОЧНОГО МОНИТОРИРОВАНИЯ ГЛИКЕМИИ
by: А. М. Шилов, et al.
Published: (2012-08-01)

Effect of adipose tissue deposition on insulin resistance in middle‐aged and elderly women: Based on QCT and MRI mDIXON‐Quant
by: Ying Liu, et al.
Published: (2025-02-01)

Association between triglyceride-glucose index and the risk of type 2 diabetes mellitus
by: Hui Luo, et al.
Published: (2025-05-01)

Metformin effects to carbohydrate and lipids metabolism in impaired glucose tolerance patients.
by: Alexander Vasil'evich Dreval', et al.
Published: (2010-06-01)

Use of continuous subcutaneous insulin infusion by a portable insulin pump during pregnancy in women with type 1 diabetes mellitus
by: Zorić Svetlana, et al.
Published: (2006-01-01)

Severity of carbohydrate metabolism disturbances, arterial hypertension stage, and lipid profile in patients with metabolic syndrome
by: Yu. V. Zhernakova, et al.
Published: (2012-04-01)

Insulin pump therapy in type 1 diabetes mellitus: education effectiveness and quality of life
by: Lyudmila Ibragimovna Ibragimova, et al.
Published: (2012-03-01)

Genetic association of type 2 diabetes mellitus and glycaemic factors with primary tumours of the central nervous system
by: Yongxue Li, et al.
Published: (2024-11-01)

Is there a correlation between blood glucose curve and the insulin resistance during oral glucose tolerance test in females suffering from polycystic ovary syndrome?
by: Spremović-Rađenović Svetlana, et al.
Published: (2021-01-01)