Morphometry in Oral Leukoplakia with Epithelial Dysplasia
<strong>Foundation</strong>: oral leukoplakia is the most common potentially malignant lesion of the oral mucous membranes and carries a proven risk of developing oral cancer. <br /><strong>Objective:</strong> to characterize oral leukoplakia according to the degree of...
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| Language: | Spanish |
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Universidad de las Ciencias Médicas de Cienfuegos
2025-05-01
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| Online Access: | https://revfinlay.sld.cu/index.php/finlay/article/view/1458 |
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| author | Yisel Alonso Vila Galia Ivis Pérez Rumbaut Pedro Augusto Díaz Rojas Laura Naranjo Hernández Yamilka Mesa González Marlén Llanes Torres |
| author_facet | Yisel Alonso Vila Galia Ivis Pérez Rumbaut Pedro Augusto Díaz Rojas Laura Naranjo Hernández Yamilka Mesa González Marlén Llanes Torres |
| author_sort | Yisel Alonso Vila |
| collection | DOAJ |
| description | <strong>Foundation</strong>: oral leukoplakia is the most common potentially malignant lesion of the oral mucous membranes and carries a proven risk of developing oral cancer. <br /><strong>Objective:</strong> to characterize oral leukoplakia according to the degree of epithelial dysplasia using morphometric and stereological parameters. <br /><strong>Method:</strong> a case series study was conducted to determine morphometric indicators of leukoplakia lesions of the oral mucosa in biopsies from patients seen in the Pathology and Maxillofacial Departments of Dr. Gustavo Aldereguía Lima General University Hospital in Cienfuegos. The sample was obtained by purposive sampling and consisted of 30 histological slides. The study variable was the morphometric characterization of leukoplakia of the oral mucosa with dysplasia. Descriptive and inferential statistics were applied. <br /><strong>Results:</strong> there was statistical significance in the nuclear shape factor; as the degree of dysplasia increased, there was a greater degree of nuclear pleomorphism. In nuclear volume, descriptive statistics showed a downward curve from mild to severe dysplasia. <br /><strong>Conclusions:</strong> as the degree of dysplasia increased, there was a greater degree of nuclear pleomorphism. Descriptive statistics showed a downward curve from mild to severe dysplasia. |
| format | Article |
| id | doaj-art-9c2b70ea23da4b6aaa66e2b0dc0ea81e |
| institution | Kabale University |
| issn | 2221-2434 |
| language | Spanish |
| publishDate | 2025-05-01 |
| publisher | Universidad de las Ciencias Médicas de Cienfuegos |
| record_format | Article |
| series | Revista Finlay |
| spelling | doaj-art-9c2b70ea23da4b6aaa66e2b0dc0ea81e2025-08-20T03:27:51ZspaUniversidad de las Ciencias Médicas de CienfuegosRevista Finlay2221-24342025-05-01150e1458e1458760Morphometry in Oral Leukoplakia with Epithelial DysplasiaYisel Alonso Vila0Galia Ivis Pérez Rumbaut1Pedro Augusto Díaz Rojas2Laura Naranjo Hernández3Yamilka Mesa González4Marlén Llanes Torres5Universidad de Ciencias Médicas de Cienfuegos. Cienfuegos.Universidad de Ciencias Médicas de Cienfuegos. Cienfuegos.Universidad de Ciencias Médicas de Holguín. Holguín.Universidad de Ciencias Médicas de Cienfuegos. Cienfuegos.Universidad de Ciencias Médicas de Cienfuegos. Cienfuegos.Universidad de Ciencias Médicas de Cienfuegos. Cienfuegos.<strong>Foundation</strong>: oral leukoplakia is the most common potentially malignant lesion of the oral mucous membranes and carries a proven risk of developing oral cancer. <br /><strong>Objective:</strong> to characterize oral leukoplakia according to the degree of epithelial dysplasia using morphometric and stereological parameters. <br /><strong>Method:</strong> a case series study was conducted to determine morphometric indicators of leukoplakia lesions of the oral mucosa in biopsies from patients seen in the Pathology and Maxillofacial Departments of Dr. Gustavo Aldereguía Lima General University Hospital in Cienfuegos. The sample was obtained by purposive sampling and consisted of 30 histological slides. The study variable was the morphometric characterization of leukoplakia of the oral mucosa with dysplasia. Descriptive and inferential statistics were applied. <br /><strong>Results:</strong> there was statistical significance in the nuclear shape factor; as the degree of dysplasia increased, there was a greater degree of nuclear pleomorphism. In nuclear volume, descriptive statistics showed a downward curve from mild to severe dysplasia. <br /><strong>Conclusions:</strong> as the degree of dysplasia increased, there was a greater degree of nuclear pleomorphism. Descriptive statistics showed a downward curve from mild to severe dysplasia.https://revfinlay.sld.cu/index.php/finlay/article/view/1458mucosa bucalleucoplasia bucaldisplasia |
| spellingShingle | Yisel Alonso Vila Galia Ivis Pérez Rumbaut Pedro Augusto Díaz Rojas Laura Naranjo Hernández Yamilka Mesa González Marlén Llanes Torres Morphometry in Oral Leukoplakia with Epithelial Dysplasia Revista Finlay mucosa bucal leucoplasia bucal displasia |
| title | Morphometry in Oral Leukoplakia with Epithelial Dysplasia |
| title_full | Morphometry in Oral Leukoplakia with Epithelial Dysplasia |
| title_fullStr | Morphometry in Oral Leukoplakia with Epithelial Dysplasia |
| title_full_unstemmed | Morphometry in Oral Leukoplakia with Epithelial Dysplasia |
| title_short | Morphometry in Oral Leukoplakia with Epithelial Dysplasia |
| title_sort | morphometry in oral leukoplakia with epithelial dysplasia |
| topic | mucosa bucal leucoplasia bucal displasia |
| url | https://revfinlay.sld.cu/index.php/finlay/article/view/1458 |
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