Audit of failure rate of Coartem to treat falciparum malaria at single fourteen day follow up
Objective: To assess the failure rate of the new first line treatment regime for uncomplicated falciparum malaria in KwaZulu-Natal of Coartem tablets (20mg aftemether and 120mg lumefantrine - Novartis South Africa (PTY Ltd. Design: A before-after study. Setting: Ndumo Clinic, Ingwavuma District, K...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
AOSIS
2002-03-01
|
| Series: | South African Family Practice |
| Subjects: | |
| Online Access: | https://safpj.co.za/index.php/safpj/article/view/2055 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Objective: To assess the failure rate of the new first line treatment regime for uncomplicated falciparum malaria in KwaZulu-Natal of Coartem tablets (20mg aftemether and 120mg lumefantrine - Novartis South Africa (PTY Ltd.
Design: A before-after study.
Setting: Ndumo Clinic, Ingwavuma District, Kwazulu-Natal, South Africa, February 2001.
Study Group: 67 patients presenting to Ndumo clinic with uncomplicated malaria, diagnosed by symptoms and positive immunochromographic test for plasmodium falciparum.
Main outcome measures: All 58 follow-up slides obtained were negative. 8 patients failed to return, and 1 slide washed off. Only 43 smears were positive at day 0 of which 36 had follow-up smears.
Conclusions: No resistance to Coartem was shown at day 4, and Coartem has been shown to be more effective at clearing falciparum malaria parasites than a previous regime of sulfadoxine/pyrimethamine with chlorine. |
|---|---|
| ISSN: | 2078-6190 2078-6204 |