Severe Cholestasis and Bile Cast Nephropathy Induced by Anabolic Steroids Successfully Treated with Plasma Exchange
We report a case of a bodybuilder who took a regimen of anabolic steroids containing stanozolol and testosterone propionate for 8 weeks which led to the development of jaundice and severe pruritus with serum total bilirubin reaching 41.22 mg/dL. Despite supportive care with fluid and albumin therapy...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2017/4296474 |
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| _version_ | 1850171426452013056 |
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| author | Christelle El Khoury Toni Sabbouh Hussein Farhat Antoine Ferzli |
| author_facet | Christelle El Khoury Toni Sabbouh Hussein Farhat Antoine Ferzli |
| author_sort | Christelle El Khoury |
| collection | DOAJ |
| description | We report a case of a bodybuilder who took a regimen of anabolic steroids containing stanozolol and testosterone propionate for 8 weeks which led to the development of jaundice and severe pruritus with serum total bilirubin reaching 41.22 mg/dL. Despite supportive care with fluid and albumin therapy, serum creatinine was progressively increasing. He underwent 6 successful sessions of plasma exchange (PE) with marked improvement at the end of the sessions. Three months after discharge, the patient’s creatinine and total bilirubin levels were 1.08 mg/dL and 1.2 mg/dL, respectively. |
| format | Article |
| id | doaj-art-9c1aa056a7d343d69601f6a94ff3154a |
| institution | OA Journals |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-9c1aa056a7d343d69601f6a94ff3154a2025-08-20T02:20:16ZengWileyCase Reports in Medicine1687-96271687-96352017-01-01201710.1155/2017/42964744296474Severe Cholestasis and Bile Cast Nephropathy Induced by Anabolic Steroids Successfully Treated with Plasma ExchangeChristelle El Khoury0Toni Sabbouh1Hussein Farhat2Antoine Ferzli3Family Medicine Division, Lebanese American University Medical Center, Beirut, LebanonInternal Medicine Division, Morristown Medical Center, Morristown, NJ, USALaboratory Medicine Division, Lebanese American University Medical Center, Beirut, LebanonGastroenterology Division, Lebanese American University Medical Center, Beirut, LebanonWe report a case of a bodybuilder who took a regimen of anabolic steroids containing stanozolol and testosterone propionate for 8 weeks which led to the development of jaundice and severe pruritus with serum total bilirubin reaching 41.22 mg/dL. Despite supportive care with fluid and albumin therapy, serum creatinine was progressively increasing. He underwent 6 successful sessions of plasma exchange (PE) with marked improvement at the end of the sessions. Three months after discharge, the patient’s creatinine and total bilirubin levels were 1.08 mg/dL and 1.2 mg/dL, respectively.http://dx.doi.org/10.1155/2017/4296474 |
| spellingShingle | Christelle El Khoury Toni Sabbouh Hussein Farhat Antoine Ferzli Severe Cholestasis and Bile Cast Nephropathy Induced by Anabolic Steroids Successfully Treated with Plasma Exchange Case Reports in Medicine |
| title | Severe Cholestasis and Bile Cast Nephropathy Induced by Anabolic Steroids Successfully Treated with Plasma Exchange |
| title_full | Severe Cholestasis and Bile Cast Nephropathy Induced by Anabolic Steroids Successfully Treated with Plasma Exchange |
| title_fullStr | Severe Cholestasis and Bile Cast Nephropathy Induced by Anabolic Steroids Successfully Treated with Plasma Exchange |
| title_full_unstemmed | Severe Cholestasis and Bile Cast Nephropathy Induced by Anabolic Steroids Successfully Treated with Plasma Exchange |
| title_short | Severe Cholestasis and Bile Cast Nephropathy Induced by Anabolic Steroids Successfully Treated with Plasma Exchange |
| title_sort | severe cholestasis and bile cast nephropathy induced by anabolic steroids successfully treated with plasma exchange |
| url | http://dx.doi.org/10.1155/2017/4296474 |
| work_keys_str_mv | AT christelleelkhoury severecholestasisandbilecastnephropathyinducedbyanabolicsteroidssuccessfullytreatedwithplasmaexchange AT tonisabbouh severecholestasisandbilecastnephropathyinducedbyanabolicsteroidssuccessfullytreatedwithplasmaexchange AT husseinfarhat severecholestasisandbilecastnephropathyinducedbyanabolicsteroidssuccessfullytreatedwithplasmaexchange AT antoineferzli severecholestasisandbilecastnephropathyinducedbyanabolicsteroidssuccessfullytreatedwithplasmaexchange |