Green biogenic fabrication of AgNPs derived from Pulicaria jaubertii leaf extract: Investigation of antimicrobial and cytotoxic properties
''Plant-mediated synthesis of nanomaterials offers an eco-friendly and cost-effective alternative for biomedical applications. In this study, silver nanoparticles (AgNPs) were green-synthesized using a leaf extract of Pulicaria jaubertii, which served as both a reducing and stabilizing age...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-07-01
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| Series: | OpenNano |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352952025000179 |
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| Summary: | ''Plant-mediated synthesis of nanomaterials offers an eco-friendly and cost-effective alternative for biomedical applications. In this study, silver nanoparticles (AgNPs) were green-synthesized using a leaf extract of Pulicaria jaubertii, which served as both a reducing and stabilizing agent. The biophysical characterization of synthesized AgNPs confirmed their successful fabrication through Ultraviolet-Visible spectroscopy, Dynamic Light Scattering, Fourier Transform Infrared spectroscopy, Transmission Electron Microscopy, and Scanning Electron Microscope- Energy Dispersive X-ray Analysis. The synthesized AgNPs demonstrated potent antibacterial activity against gram-negative (Escherichia coli) and gram-positive (Staphylococcus aureus) pathogens, as evidenced by agar well diffusion, time-kill, and antibiofilm assays. Notably, the nanoparticles exhibited minimal cytotoxicity toward Peripheral Blood Mononuclear Cells and Human Red Blood Cells, underscoring their biocompatibility. These findings highlight the potential of Pulicaria jaubertii-derived AgNPs as promising candidates for antimicrobial therapies and biomedical applications.'' |
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| ISSN: | 2352-9520 |