Antibacterial properties of the aqueous extract of Hypericum coris and relative purification of its antibacterial compounds
Introduction: Hypericum coris is used in western Iran for wound disinfection. This study aimed to investigate the antibacterial properties of the aqueous extract of this plant against certain pathogenic bacteria and to purify its antibacterial compounds partially. Materials & Methods: The aeria...
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Ilam University of Medical Sciences
2025-07-01
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| Series: | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām |
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| Online Access: | http://sjimu.medilam.ac.ir/article-1-8512-en.pdf |
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| author | Ali Mirzaei Shahriar Saeidian Hamid Darvishnia Parastoo Mardani Amirarsalan Kavyanifard |
| author_facet | Ali Mirzaei Shahriar Saeidian Hamid Darvishnia Parastoo Mardani Amirarsalan Kavyanifard |
| author_sort | Ali Mirzaei |
| collection | DOAJ |
| description | Introduction: Hypericum coris is used in western Iran for wound disinfection. This study aimed to investigate the antibacterial properties of the aqueous extract of this plant against certain pathogenic bacteria and to purify its antibacterial compounds partially.
Materials & Methods: The aerial parts of the plant were extracted using maceration. The antibacterial characteristics of the extract were evaluated against common wound infection-causing bacteria using disk diffusion and MIC. To partially purify the antibacterial compounds, the extract was subjected to various solvents, and each fraction was assessed for its antibacterial properties. Data analysis was conducted using one-way analysis of variance (ANOVA), and means were compared using Duncan's multiple range test. It was performed using SPSS V.18 at a significance level (p≥0.05).
Results: The findings indicated that the aqueous extract was effective against all the studied bacteria, with a greater impact on Gram-positive bacteria. It was also determined that only the polar fractions have antibacterial activity, and their antibacterial potency increased as polarity increased.
Conclusion: This was the first report on the effects of the aqueous extract of H. coris on pathogenic bacteria, demonstrating that this extract is effective against all studied bacterial strains. Additionally, it was found that the antibacterial compounds present in the extract are polar. |
| format | Article |
| id | doaj-art-9c0206660de84a54a38b19c43fbe558b |
| institution | Kabale University |
| issn | 1563-4728 2588-3135 |
| language | fas |
| publishDate | 2025-07-01 |
| publisher | Ilam University of Medical Sciences |
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| series | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām |
| spelling | doaj-art-9c0206660de84a54a38b19c43fbe558b2025-08-25T07:35:14ZfasIlam University of Medical SciencesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām1563-47282588-31352025-07-013336781Antibacterial properties of the aqueous extract of Hypericum coris and relative purification of its antibacterial compoundsAli Mirzaei0Shahriar Saeidian1Hamid Darvishnia2Parastoo Mardani3Amirarsalan Kavyanifard4 Dept of Biology, Payam Noor University, Tehran, 1395-4697, Iran Dept of Biology, Payam Noor University, Tehran, 1395-4697, Iran Dept of Biology, Payam Noor University, Tehran, 1395-4697, Iran Dept of Biology, Payam Noor University, Tehran, 1395-4697, Iran Dept of Biology, Payam Noor University, Tehran, 1395-4697, Iran Introduction: Hypericum coris is used in western Iran for wound disinfection. This study aimed to investigate the antibacterial properties of the aqueous extract of this plant against certain pathogenic bacteria and to purify its antibacterial compounds partially. Materials & Methods: The aerial parts of the plant were extracted using maceration. The antibacterial characteristics of the extract were evaluated against common wound infection-causing bacteria using disk diffusion and MIC. To partially purify the antibacterial compounds, the extract was subjected to various solvents, and each fraction was assessed for its antibacterial properties. Data analysis was conducted using one-way analysis of variance (ANOVA), and means were compared using Duncan's multiple range test. It was performed using SPSS V.18 at a significance level (p≥0.05). Results: The findings indicated that the aqueous extract was effective against all the studied bacteria, with a greater impact on Gram-positive bacteria. It was also determined that only the polar fractions have antibacterial activity, and their antibacterial potency increased as polarity increased. Conclusion: This was the first report on the effects of the aqueous extract of H. coris on pathogenic bacteria, demonstrating that this extract is effective against all studied bacterial strains. Additionally, it was found that the antibacterial compounds present in the extract are polar.http://sjimu.medilam.ac.ir/article-1-8512-en.pdfpathogen bacteriaantibacterial compoundsaqueous extracthypericum coris |
| spellingShingle | Ali Mirzaei Shahriar Saeidian Hamid Darvishnia Parastoo Mardani Amirarsalan Kavyanifard Antibacterial properties of the aqueous extract of Hypericum coris and relative purification of its antibacterial compounds Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām pathogen bacteria antibacterial compounds aqueous extract hypericum coris |
| title | Antibacterial properties of the aqueous extract of Hypericum coris and relative purification of its antibacterial compounds |
| title_full | Antibacterial properties of the aqueous extract of Hypericum coris and relative purification of its antibacterial compounds |
| title_fullStr | Antibacterial properties of the aqueous extract of Hypericum coris and relative purification of its antibacterial compounds |
| title_full_unstemmed | Antibacterial properties of the aqueous extract of Hypericum coris and relative purification of its antibacterial compounds |
| title_short | Antibacterial properties of the aqueous extract of Hypericum coris and relative purification of its antibacterial compounds |
| title_sort | antibacterial properties of the aqueous extract of hypericum coris and relative purification of its antibacterial compounds |
| topic | pathogen bacteria antibacterial compounds aqueous extract hypericum coris |
| url | http://sjimu.medilam.ac.ir/article-1-8512-en.pdf |
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