The effects of incremental aerobic training and electrical stimulation on sexual biomarkers in infarcted rats
Background and aims: Sexual dysfunction is a prevalent issue among cardiovascular patients, particularly those who have experienced myocardial infarction, and it can be influenced by exercise. This study...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | fas |
| Published: |
Iran Air Force Health Administration
2024-12-01
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| Series: | فصلنامه ابن سینا |
| Subjects: | |
| Online Access: | http://ebnesina.ajaums.ac.ir/article-1-1349-en.pdf |
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| Summary: | Background and aims: Sexual dysfunction is a prevalent issue among cardiovascular patients, particularly those who have experienced myocardial infarction, and it can be influenced by exercise. This study aimed to investigate the effects of aerobic exercise combined with electrical stimulation on sexual biomarkers in infarcted rats.
Methods: In this controlled experimental study, 28 male Wistar rats aged eight weeks were randomly assigned to four groups: control, exercise, electrical stimulation, and exercise+electrical stimulation, following myocardial infarction induced by isoproterenol (ISO) at a dose of 150 mg/kg. The intervention groups engaged in exercise at speeds of 10 to 18 m/min for 50 minutes and electrical stimulation via foot shock at an intensity of 0.5 mA for 20 minutes. After the interventions and subsequent anesthesia, plasma levels of testosterone and gonadotropin-releasing hormone (GnRH) were measured using ELISA.
Results: The results demonstrated a non-significant increase in plasma testosterone levels (p = 0.398) in the exercise group compared to the control group. However, significant changes were observed in plasma levels of GnRH (p < 0.0001).
Conclusion: Aerobic exercise appears to be an effective and beneficial intervention for alleviating sexual dysfunction in infarcted rats by inducing positive changes in sexual biomarkers. |
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| ISSN: | 1735-9503 2645-4653 |