The role of inflammation in pathogenesis and treatment of colorectal cancer

One of the factors affecting the effectiveness of treatment and determining the prognosis of a patient with colorectal cancer may be inflammatory status both before and after surgical treatment. The review is devoted to the description of possible mechanisms of relationa between patient's infla...

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Main Authors: T. N. Garmanova, M. I. Bredikhin, I. A. Tulina, P. V. Tsarkov
Format: Article
Language:Russian
Published: QUASAR, LLC 2018-12-01
Series:Исследования и практика в медицине
Subjects:
Online Access:https://www.rpmj.ru/rpmj/article/view/320
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author T. N. Garmanova
M. I. Bredikhin
I. A. Tulina
P. V. Tsarkov
author_facet T. N. Garmanova
M. I. Bredikhin
I. A. Tulina
P. V. Tsarkov
author_sort T. N. Garmanova
collection DOAJ
description One of the factors affecting the effectiveness of treatment and determining the prognosis of a patient with colorectal cancer may be inflammatory status both before and after surgical treatment. The review is devoted to the description of possible mechanisms of relationa between patient's inflammatory status and oncogenesis. Particular attention is paid to the ability of tumor cells to modify the immune cells from the antioncogenic to prooncogenic status. The paper makes an attempt to present a unified concept of the impact of postoperative complications on tumor recurrence in the light of the inflammatory response to surgical intervention.
format Article
id doaj-art-9bf4c4592dab4266b52ddc3bc3850bca
institution DOAJ
issn 2410-1893
language Russian
publishDate 2018-12-01
publisher QUASAR, LLC
record_format Article
series Исследования и практика в медицине
spelling doaj-art-9bf4c4592dab4266b52ddc3bc3850bca2025-08-20T03:00:57ZrusQUASAR, LLCИсследования и практика в медицине2410-18932018-12-0154364510.17709/2409-2231-2018-5-4-4232The role of inflammation in pathogenesis and treatment of colorectal cancerT. N. Garmanova0M. I. Bredikhin1I. A. Tulina2P. V. Tsarkov3Clinic of Colorectal and Minimally Invasive Surgery of Sechenov First Moscow State Medical University (Sechenov University)Clinic of Colorectal and Minimally Invasive Surgery of Sechenov First Moscow State Medical University (Sechenov University)Clinic of Colorectal and Minimally Invasive Surgery of Sechenov First Moscow State Medical University (Sechenov University)Clinic of Colorectal and Minimally Invasive Surgery of Sechenov First Moscow State Medical University (Sechenov University)One of the factors affecting the effectiveness of treatment and determining the prognosis of a patient with colorectal cancer may be inflammatory status both before and after surgical treatment. The review is devoted to the description of possible mechanisms of relationa between patient's inflammatory status and oncogenesis. Particular attention is paid to the ability of tumor cells to modify the immune cells from the antioncogenic to prooncogenic status. The paper makes an attempt to present a unified concept of the impact of postoperative complications on tumor recurrence in the light of the inflammatory response to surgical intervention.https://www.rpmj.ru/rpmj/article/view/320colorectal canceroncogenesisinflammatory statusinfectious complicationsdisease prognosisrecurrence
spellingShingle T. N. Garmanova
M. I. Bredikhin
I. A. Tulina
P. V. Tsarkov
The role of inflammation in pathogenesis and treatment of colorectal cancer
Исследования и практика в медицине
colorectal cancer
oncogenesis
inflammatory status
infectious complications
disease prognosis
recurrence
title The role of inflammation in pathogenesis and treatment of colorectal cancer
title_full The role of inflammation in pathogenesis and treatment of colorectal cancer
title_fullStr The role of inflammation in pathogenesis and treatment of colorectal cancer
title_full_unstemmed The role of inflammation in pathogenesis and treatment of colorectal cancer
title_short The role of inflammation in pathogenesis and treatment of colorectal cancer
title_sort role of inflammation in pathogenesis and treatment of colorectal cancer
topic colorectal cancer
oncogenesis
inflammatory status
infectious complications
disease prognosis
recurrence
url https://www.rpmj.ru/rpmj/article/view/320
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