Diagnostic accuracy of increased C reactive protein levels in distal ureteric stone ejection prediction using a CT scan as the gold standard
BACKGROUND AND OBJECTIVES: Numerous clinical urological diseases have been shown to benefit from CRP, such as the evaluation of renal injury in pyelonephritis, the determination of the severity of pediatric UTIs, and the prevention of voiding cystourethrography in cases of pediatric UTIs and vesico...
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University of Faisalabad
2025-02-01
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| Series: | Journal of University Medical & Dental College |
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| Online Access: | https://www.jumdc.com/index.php/jumdc/article/view/955 |
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| author | Mudassar Saeed Pansota Muhammad Shahzad Saleem Burhan Barkat Asra Aleem Mumtaz Rasool |
| author_facet | Mudassar Saeed Pansota Muhammad Shahzad Saleem Burhan Barkat Asra Aleem Mumtaz Rasool |
| author_sort | Mudassar Saeed Pansota |
| collection | DOAJ |
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BACKGROUND AND OBJECTIVES: Numerous clinical urological diseases have been shown to benefit from CRP, such as the evaluation of renal injury in pyelonephritis, the determination of the severity of pediatric UTIs, and the prevention of voiding cystourethrography in cases of pediatric UTIs and vesicoureteral reflux. This study has been conducted to diagnose the accuracy of increased C reactive protein levels in distal ureteric stones.
METHODOLOGY: In total, 184 individuals with single distal ureteric stones were included. Patients with severe hydronephrosis, multiple ureteral stones, impaired renal function, pregnancy, single kidney, endoscopic procedures, or prior ureteric surgery history or concomitant ureteric anomalies were excluded. Each patient had a blood sample sent to the hospital laboratory to evaluate the serum levels of CRP (c-reactive protein). For four weeks, the researcher checked in with each patient once a week. After that, each patient had computed tomography, and the data was evaluated to determine whether or not ureteric stones were present.
RESULTS: The overall sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of elevated C reactive protein levels are 92.39%, 95.51%, 92.63%, and 94.02%, respectively, when using a CT scan as the gold standard to predict the ejection of a distal ureteric stone (p-value = 0.0001).
CONCLUSION: This study found that elevated C reactive protein levels have a fairly high diagnostic accuracy in predicting the ejection of distal ureteric stones.
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| format | Article |
| id | doaj-art-9bf2e6e603314ec2ad4e4a0dc13c93a3 |
| institution | DOAJ |
| issn | 2221-7827 2310-5542 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | University of Faisalabad |
| record_format | Article |
| series | Journal of University Medical & Dental College |
| spelling | doaj-art-9bf2e6e603314ec2ad4e4a0dc13c93a32025-08-20T03:15:26ZengUniversity of FaisalabadJournal of University Medical & Dental College2221-78272310-55422025-02-0116110.37723/jumdc.v16i1.955Diagnostic accuracy of increased C reactive protein levels in distal ureteric stone ejection prediction using a CT scan as the gold standardMudassar Saeed Pansota0Muhammad Shahzad Saleem1Burhan Barkat2Asra Aleem3Mumtaz Rasool4Assistant Professor, Department of Urology, Shahida Islam Medical College, Lodhran.Assistant Professor, Department of Urology, DG Khan Medical College & Teaching Hospital, DG Khan.Senior Registrar, Department of Urology, BahaWal Victoria Hospital/Quaid-e-Azam Medical College, Bahawalpur.Senior Assistant Professor ,Department of Urology, BahaWal Victoria Hospital/Quaid-e-Azam Medical College, Bahawalpur.Professor, Department of Urology, BahaWal Victoria Hospital/Quaid-e-Azam Medical College, Bahawalpur. BACKGROUND AND OBJECTIVES: Numerous clinical urological diseases have been shown to benefit from CRP, such as the evaluation of renal injury in pyelonephritis, the determination of the severity of pediatric UTIs, and the prevention of voiding cystourethrography in cases of pediatric UTIs and vesicoureteral reflux. This study has been conducted to diagnose the accuracy of increased C reactive protein levels in distal ureteric stones. METHODOLOGY: In total, 184 individuals with single distal ureteric stones were included. Patients with severe hydronephrosis, multiple ureteral stones, impaired renal function, pregnancy, single kidney, endoscopic procedures, or prior ureteric surgery history or concomitant ureteric anomalies were excluded. Each patient had a blood sample sent to the hospital laboratory to evaluate the serum levels of CRP (c-reactive protein). For four weeks, the researcher checked in with each patient once a week. After that, each patient had computed tomography, and the data was evaluated to determine whether or not ureteric stones were present. RESULTS: The overall sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of elevated C reactive protein levels are 92.39%, 95.51%, 92.63%, and 94.02%, respectively, when using a CT scan as the gold standard to predict the ejection of a distal ureteric stone (p-value = 0.0001). CONCLUSION: This study found that elevated C reactive protein levels have a fairly high diagnostic accuracy in predicting the ejection of distal ureteric stones. https://www.jumdc.com/index.php/jumdc/article/view/955UretericStoneExpulsionC-reactive ProteinSensitivity |
| spellingShingle | Mudassar Saeed Pansota Muhammad Shahzad Saleem Burhan Barkat Asra Aleem Mumtaz Rasool Diagnostic accuracy of increased C reactive protein levels in distal ureteric stone ejection prediction using a CT scan as the gold standard Journal of University Medical & Dental College Ureteric Stone Expulsion C-reactive Protein Sensitivity |
| title | Diagnostic accuracy of increased C reactive protein levels in distal ureteric stone ejection prediction using a CT scan as the gold standard |
| title_full | Diagnostic accuracy of increased C reactive protein levels in distal ureteric stone ejection prediction using a CT scan as the gold standard |
| title_fullStr | Diagnostic accuracy of increased C reactive protein levels in distal ureteric stone ejection prediction using a CT scan as the gold standard |
| title_full_unstemmed | Diagnostic accuracy of increased C reactive protein levels in distal ureteric stone ejection prediction using a CT scan as the gold standard |
| title_short | Diagnostic accuracy of increased C reactive protein levels in distal ureteric stone ejection prediction using a CT scan as the gold standard |
| title_sort | diagnostic accuracy of increased c reactive protein levels in distal ureteric stone ejection prediction using a ct scan as the gold standard |
| topic | Ureteric Stone Expulsion C-reactive Protein Sensitivity |
| url | https://www.jumdc.com/index.php/jumdc/article/view/955 |
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