Research progress on the mechanism of long non-coding RNA LINC00641 in the development of malignant tumors
Long non-coding RNAs (lncRNAs) are a class of functional RNA that is not translated into proteins, with more than 200 nucleotides in length. LncRNAs are involved in the regulation of gene expression at the transcriptional, and post-transcriptional levels. In recent years, more and more evidence has...
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| Format: | Article |
| Language: | zho |
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Editorial Office of New Medicine
2024-01-01
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| Series: | Yixue xinzhi zazhi |
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| Online Access: | https://yxxz.whuznhmedj.com/futureApi/storage/attach/2401/kRT3YxZFEooTe0IiaIchzPSC8QnhSOiSCXT1rCdM.pdf |
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| author | GUO Mengmeng MING Daojing REN Yiming QIAN Xinhang YANG Shisong WANG Congcong LU Peiwen ZHANG Jinhui YUAN Shuai XI Shu ZENG Xiantao |
| author_facet | GUO Mengmeng MING Daojing REN Yiming QIAN Xinhang YANG Shisong WANG Congcong LU Peiwen ZHANG Jinhui YUAN Shuai XI Shu ZENG Xiantao |
| author_sort | GUO Mengmeng |
| collection | DOAJ |
| description | Long non-coding RNAs (lncRNAs) are a class of functional RNA that is not translated into proteins, with more than 200 nucleotides in length. LncRNAs are involved in the regulation of gene expression at the transcriptional, and post-transcriptional levels. In recent years, more and more evidence has shown that lncRNAs regulate the biological processes of tumor proliferation, apoptosis, invasion and metastasis by various signaling pathways. LINC00641, located on human chromosome 14q11.2, is differentially expressed in a variety of tumors tissues and is associated with prognosis of tumor. Changes in the expression of LINC00641 can lead to alterations in various biological behaviors of tumor cells. Therefore, LINC00641 could be a new biomarker and potential target in clinical practice. We reviewed the biological function, molecular mechanism and clinical significance of LINC00641 in various human malignant tumors. |
| format | Article |
| id | doaj-art-9be835a4f08f4c729e1e49a2b65a5cc7 |
| institution | OA Journals |
| issn | 1004-5511 |
| language | zho |
| publishDate | 2024-01-01 |
| publisher | Editorial Office of New Medicine |
| record_format | Article |
| series | Yixue xinzhi zazhi |
| spelling | doaj-art-9be835a4f08f4c729e1e49a2b65a5cc72025-08-20T01:59:57ZzhoEditorial Office of New MedicineYixue xinzhi zazhi1004-55112024-01-01341889810.12173/j.issn.1004-5511.2023110356437Research progress on the mechanism of long non-coding RNA LINC00641 in the development of malignant tumorsGUO MengmengMING DaojingREN YimingQIAN XinhangYANG ShisongWANG CongcongLU PeiwenZHANG JinhuiYUAN ShuaiXI ShuZENG XiantaoLong non-coding RNAs (lncRNAs) are a class of functional RNA that is not translated into proteins, with more than 200 nucleotides in length. LncRNAs are involved in the regulation of gene expression at the transcriptional, and post-transcriptional levels. In recent years, more and more evidence has shown that lncRNAs regulate the biological processes of tumor proliferation, apoptosis, invasion and metastasis by various signaling pathways. LINC00641, located on human chromosome 14q11.2, is differentially expressed in a variety of tumors tissues and is associated with prognosis of tumor. Changes in the expression of LINC00641 can lead to alterations in various biological behaviors of tumor cells. Therefore, LINC00641 could be a new biomarker and potential target in clinical practice. We reviewed the biological function, molecular mechanism and clinical significance of LINC00641 in various human malignant tumors.https://yxxz.whuznhmedj.com/futureApi/storage/attach/2401/kRT3YxZFEooTe0IiaIchzPSC8QnhSOiSCXT1rCdM.pdflong non-coding rnaslinc00641malignant tumor |
| spellingShingle | GUO Mengmeng MING Daojing REN Yiming QIAN Xinhang YANG Shisong WANG Congcong LU Peiwen ZHANG Jinhui YUAN Shuai XI Shu ZENG Xiantao Research progress on the mechanism of long non-coding RNA LINC00641 in the development of malignant tumors Yixue xinzhi zazhi long non-coding rnas linc00641 malignant tumor |
| title | Research progress on the mechanism of long non-coding RNA LINC00641 in the development of malignant tumors |
| title_full | Research progress on the mechanism of long non-coding RNA LINC00641 in the development of malignant tumors |
| title_fullStr | Research progress on the mechanism of long non-coding RNA LINC00641 in the development of malignant tumors |
| title_full_unstemmed | Research progress on the mechanism of long non-coding RNA LINC00641 in the development of malignant tumors |
| title_short | Research progress on the mechanism of long non-coding RNA LINC00641 in the development of malignant tumors |
| title_sort | research progress on the mechanism of long non coding rna linc00641 in the development of malignant tumors |
| topic | long non-coding rnas linc00641 malignant tumor |
| url | https://yxxz.whuznhmedj.com/futureApi/storage/attach/2401/kRT3YxZFEooTe0IiaIchzPSC8QnhSOiSCXT1rCdM.pdf |
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