Mechanistic Studies on the Role of IL-17/NLRP3 in Arsenic-Induced Activation of Hepatic Stellate Cells Through Hepatocyte Proptosis

Mechanistic Studies on the Role of IL-17/NLRP3 in Arsenic-Induced Activation of Hepatic Stellate Cells Through Hepatocyte Proptosis

Long-term exposure to arsenic, a prevalent environmental contaminant, has been implicated in the pathogenesis of various hepatic conditions. Hepatic stellate cells (HSCs) are central to the development of liver fibrosis. Recently, the involvement of interleukin-17 (IL-17) and the NOD-like receptor p...

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Bibliographic Details
Main Authors: Ting Hu, Mei Chen, Sai Tian, Peng Luo, Jiangping Zhang
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Toxics
Subjects:
arsenic
pyroptosis
IL-17
NLRP3
HSCs
Online Access:https://www.mdpi.com/2305-6304/13/4/287
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