Analysis based on osmoregulatory enzymes and LC-MS technology for the adaptation of antennal gland of mud crabs (Scylla paramamosain) to acute chloride type low-salt saline-alkali water stress

The mud crab (Scylla paramamosain) is an important species for seawater aquaculture, the utilization of saline-alkali water provides potential for the further development of the mud crab industry, but the adaptation mechanism of the antennal gland to chloride type low-salt saline-alkali water has no...

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Main Authors: Jinwei Wang, Kangxiang Qin, Chunlin Wang, Changkao Mu, Huan Wang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Aquaculture Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352513424004824
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author Jinwei Wang
Kangxiang Qin
Chunlin Wang
Changkao Mu
Huan Wang
author_facet Jinwei Wang
Kangxiang Qin
Chunlin Wang
Changkao Mu
Huan Wang
author_sort Jinwei Wang
collection DOAJ
description The mud crab (Scylla paramamosain) is an important species for seawater aquaculture, the utilization of saline-alkali water provides potential for the further development of the mud crab industry, but the adaptation mechanism of the antennal gland to chloride type low-salt saline-alkali water has not been fully studied. In this study, we evaluated the osmoregulatory enzyme activity (n=3) and metabolic changes (n = 5) of the antennal gland in S. paramamosain after a sudden drop in salinity from 23 ‰ of seawater to 2 ‰ of chloride type low-salt saline-alkali water. After the decrease in salinity, the activity of osmoregulatory enzymes in the antennal gland, including Na+/K+-ATPase, NKCC, carbonic anhydrase (CA), and V-ATPase showed a trend of first increasing and then decreasing. Through LC-MS technology, we identified 308 differential metabolites. In addition, KEGG enrichment analysis identified eight significant metabolic pathways (P<0.05), primarily related to amino acid metabolism, signaling pathways, and lipid metabolism. Among them, amino acid and energy metabolism occupy the majority, followed by lipid metabolism pathways. Our research results indicate that amino acids and energy metabolism are involved in the adaptation of the antennal gland of the mud crab to acute chloride type low-salt saline-alkali water stress, in which lipid metabolites play an important supportive role.
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spelling doaj-art-9be33fd9e6ea4c87bcc4c90e1d27aa012025-08-20T02:51:30ZengElsevierAquaculture Reports2352-51342024-12-013910239410.1016/j.aqrep.2024.102394Analysis based on osmoregulatory enzymes and LC-MS technology for the adaptation of antennal gland of mud crabs (Scylla paramamosain) to acute chloride type low-salt saline-alkali water stressJinwei Wang0Kangxiang Qin1Chunlin Wang2Changkao Mu3Huan Wang4School of Marine Science, Ningbo University, Ningbo, Zhejiang, ChinaSchool of Marine Science, Ningbo University, Ningbo, Zhejiang, ChinaSchool of Marine Science, Ningbo University, Ningbo, Zhejiang, China; Key Laboratory of Aquacultral Biotechnology Ministry of Education, Ningbo University, Ningbo, Zhejiang, China; Corresponding authors at: School of Marine Science, Ningbo University, Ningbo, Zhejiang, China.School of Marine Science, Ningbo University, Ningbo, Zhejiang, China; Key Laboratory of Aquacultral Biotechnology Ministry of Education, Ningbo University, Ningbo, Zhejiang, ChinaSchool of Marine Science, Ningbo University, Ningbo, Zhejiang, China; Key Laboratory of Aquacultral Biotechnology Ministry of Education, Ningbo University, Ningbo, Zhejiang, China; Corresponding authors at: School of Marine Science, Ningbo University, Ningbo, Zhejiang, China.The mud crab (Scylla paramamosain) is an important species for seawater aquaculture, the utilization of saline-alkali water provides potential for the further development of the mud crab industry, but the adaptation mechanism of the antennal gland to chloride type low-salt saline-alkali water has not been fully studied. In this study, we evaluated the osmoregulatory enzyme activity (n=3) and metabolic changes (n = 5) of the antennal gland in S. paramamosain after a sudden drop in salinity from 23 ‰ of seawater to 2 ‰ of chloride type low-salt saline-alkali water. After the decrease in salinity, the activity of osmoregulatory enzymes in the antennal gland, including Na+/K+-ATPase, NKCC, carbonic anhydrase (CA), and V-ATPase showed a trend of first increasing and then decreasing. Through LC-MS technology, we identified 308 differential metabolites. In addition, KEGG enrichment analysis identified eight significant metabolic pathways (P<0.05), primarily related to amino acid metabolism, signaling pathways, and lipid metabolism. Among them, amino acid and energy metabolism occupy the majority, followed by lipid metabolism pathways. Our research results indicate that amino acids and energy metabolism are involved in the adaptation of the antennal gland of the mud crab to acute chloride type low-salt saline-alkali water stress, in which lipid metabolites play an important supportive role.http://www.sciencedirect.com/science/article/pii/S2352513424004824Scylla paramamosainAntennal glandLC-MSChloride type low-salt saline-alkali waterMetabolic mechanism
spellingShingle Jinwei Wang
Kangxiang Qin
Chunlin Wang
Changkao Mu
Huan Wang
Analysis based on osmoregulatory enzymes and LC-MS technology for the adaptation of antennal gland of mud crabs (Scylla paramamosain) to acute chloride type low-salt saline-alkali water stress
Aquaculture Reports
Scylla paramamosain
Antennal gland
LC-MS
Chloride type low-salt saline-alkali water
Metabolic mechanism
title Analysis based on osmoregulatory enzymes and LC-MS technology for the adaptation of antennal gland of mud crabs (Scylla paramamosain) to acute chloride type low-salt saline-alkali water stress
title_full Analysis based on osmoregulatory enzymes and LC-MS technology for the adaptation of antennal gland of mud crabs (Scylla paramamosain) to acute chloride type low-salt saline-alkali water stress
title_fullStr Analysis based on osmoregulatory enzymes and LC-MS technology for the adaptation of antennal gland of mud crabs (Scylla paramamosain) to acute chloride type low-salt saline-alkali water stress
title_full_unstemmed Analysis based on osmoregulatory enzymes and LC-MS technology for the adaptation of antennal gland of mud crabs (Scylla paramamosain) to acute chloride type low-salt saline-alkali water stress
title_short Analysis based on osmoregulatory enzymes and LC-MS technology for the adaptation of antennal gland of mud crabs (Scylla paramamosain) to acute chloride type low-salt saline-alkali water stress
title_sort analysis based on osmoregulatory enzymes and lc ms technology for the adaptation of antennal gland of mud crabs scylla paramamosain to acute chloride type low salt saline alkali water stress
topic Scylla paramamosain
Antennal gland
LC-MS
Chloride type low-salt saline-alkali water
Metabolic mechanism
url http://www.sciencedirect.com/science/article/pii/S2352513424004824
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