Rapidly Growing Gastrointestinal Stromal Tumor on the Esophagus
Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms that mainly occur in the stomach and small intestine; those arising in the esophagus are rarer. A 54-year-old woman was referred to our hospital with a one-month history of dysphagia. Esophagogastroduodenoscopy (EGD), performed a...
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Korean College of Helicobacter and Upper Gastrointestinal Research
2025-03-01
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| Series: | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
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| Online Access: | http://helicojournal.org/upload/pdf/kjhugr-2024-0074.pdf |
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| author | Ji Hye Park Sung Eun Kim Seun Ja Park Moo In Park Won Moon Jae Hyun Kim Kyoungwon Jung Myung Hun Lee |
| author_facet | Ji Hye Park Sung Eun Kim Seun Ja Park Moo In Park Won Moon Jae Hyun Kim Kyoungwon Jung Myung Hun Lee |
| author_sort | Ji Hye Park |
| collection | DOAJ |
| description | Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms that mainly occur in the stomach and small intestine; those arising in the esophagus are rarer. A 54-year-old woman was referred to our hospital with a one-month history of dysphagia. Esophagogastroduodenoscopy (EGD), performed approximately five months earlier, had not revealed any specific findings. However, an EGD performed in our hospital showed the presence of a round, protruding lesion (approximately 40×30 mm in size), with a normal overlying mucosal surface, 35–39 cm from the upper incisor. Chest computed tomography (CT) revealed a large esophageal mass. Enucleation was performed on the esophageal mass, and a GIST was diagnosed using immunochemical staining. Imatinib mesylate administration was initiated two months postoperatively. The patient was stable, without any evident recurrence in the 8-month postoperative follow-up EGD and chest CT examinations. Therefore, physicians should consider that patients with worsening dysphagia may have an underlying organic condition, such as an acute increase in size of an esophageal GIST, even if recent examinations were unremarkable. |
| format | Article |
| id | doaj-art-9bd5e180eca2476c9ff919fa5c320479 |
| institution | Kabale University |
| issn | 1738-3331 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Korean College of Helicobacter and Upper Gastrointestinal Research |
| record_format | Article |
| series | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
| spelling | doaj-art-9bd5e180eca2476c9ff919fa5c3204792025-08-20T03:57:08ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312025-03-01251646910.7704/kjhugr.2024.0074893Rapidly Growing Gastrointestinal Stromal Tumor on the EsophagusJi Hye Park0Sung Eun Kim1Seun Ja Park2Moo In Park3Won Moon4Jae Hyun Kim5Kyoungwon Jung6Myung Hun Lee7 Division of Gastroenterology, Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea Division of Gastroenterology, Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea Division of Gastroenterology, Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea Division of Gastroenterology, Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea Division of Gastroenterology, Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea Division of Gastroenterology, Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea Division of Gastroenterology, Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea Division of Gastroenterology, Department of Internal Medicine, Kosin University College of Medicine, Busan, KoreaGastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms that mainly occur in the stomach and small intestine; those arising in the esophagus are rarer. A 54-year-old woman was referred to our hospital with a one-month history of dysphagia. Esophagogastroduodenoscopy (EGD), performed approximately five months earlier, had not revealed any specific findings. However, an EGD performed in our hospital showed the presence of a round, protruding lesion (approximately 40×30 mm in size), with a normal overlying mucosal surface, 35–39 cm from the upper incisor. Chest computed tomography (CT) revealed a large esophageal mass. Enucleation was performed on the esophageal mass, and a GIST was diagnosed using immunochemical staining. Imatinib mesylate administration was initiated two months postoperatively. The patient was stable, without any evident recurrence in the 8-month postoperative follow-up EGD and chest CT examinations. Therefore, physicians should consider that patients with worsening dysphagia may have an underlying organic condition, such as an acute increase in size of an esophageal GIST, even if recent examinations were unremarkable.http://helicojournal.org/upload/pdf/kjhugr-2024-0074.pdfdeglutition disordersesophageal neoplasmsgastrointestinal stromal tumorsimatinib mesylate |
| spellingShingle | Ji Hye Park Sung Eun Kim Seun Ja Park Moo In Park Won Moon Jae Hyun Kim Kyoungwon Jung Myung Hun Lee Rapidly Growing Gastrointestinal Stromal Tumor on the Esophagus The Korean Journal of Helicobacter and Upper Gastrointestinal Research deglutition disorders esophageal neoplasms gastrointestinal stromal tumors imatinib mesylate |
| title | Rapidly Growing Gastrointestinal Stromal Tumor on the Esophagus |
| title_full | Rapidly Growing Gastrointestinal Stromal Tumor on the Esophagus |
| title_fullStr | Rapidly Growing Gastrointestinal Stromal Tumor on the Esophagus |
| title_full_unstemmed | Rapidly Growing Gastrointestinal Stromal Tumor on the Esophagus |
| title_short | Rapidly Growing Gastrointestinal Stromal Tumor on the Esophagus |
| title_sort | rapidly growing gastrointestinal stromal tumor on the esophagus |
| topic | deglutition disorders esophageal neoplasms gastrointestinal stromal tumors imatinib mesylate |
| url | http://helicojournal.org/upload/pdf/kjhugr-2024-0074.pdf |
| work_keys_str_mv | AT jihyepark rapidlygrowinggastrointestinalstromaltumorontheesophagus AT sungeunkim rapidlygrowinggastrointestinalstromaltumorontheesophagus AT seunjapark rapidlygrowinggastrointestinalstromaltumorontheesophagus AT mooinpark rapidlygrowinggastrointestinalstromaltumorontheesophagus AT wonmoon rapidlygrowinggastrointestinalstromaltumorontheesophagus AT jaehyunkim rapidlygrowinggastrointestinalstromaltumorontheesophagus AT kyoungwonjung rapidlygrowinggastrointestinalstromaltumorontheesophagus AT myunghunlee rapidlygrowinggastrointestinalstromaltumorontheesophagus |