Dilemma of HCV Infection in Renal Transplant Recipients

Hepatitis C virus, which usually starts during dialysis therapy, is currently the main cause of chronic liver disease in such population. The majority of patients acquired the disease through intravenous drug use or blood transfusion, with some risk factors identified. In this review we are dealing...

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Main Author: Osama Ashry Ahmed Gheith
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:International Journal of Nephrology
Online Access:http://dx.doi.org/10.4061/2011/471214
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author Osama Ashry Ahmed Gheith
author_facet Osama Ashry Ahmed Gheith
author_sort Osama Ashry Ahmed Gheith
collection DOAJ
description Hepatitis C virus, which usually starts during dialysis therapy, is currently the main cause of chronic liver disease in such population. The majority of patients acquired the disease through intravenous drug use or blood transfusion, with some risk factors identified. In this review we are dealing with the effect of renal transplantation on HCV infection and HCV-related complications after renal transplantation. Moreover, we are discussing the therapeutic options of HCV infection before and after renal transplantation, the best immunosuppressive protocol and lastly graft and patient survival in patients who underwent pretransplant management vs. those who were transplanted without treatment.
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institution Kabale University
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spelling doaj-art-9bcd9b162e8c4159b4adc4104ab0e8a22025-08-20T03:36:57ZengWileyInternational Journal of Nephrology2090-214X2090-21582011-01-01201110.4061/2011/471214471214Dilemma of HCV Infection in Renal Transplant RecipientsOsama Ashry Ahmed Gheith0Urology and Nephrology Center, Mansoura University, Gomhoria Street, Mansoura, EgyptHepatitis C virus, which usually starts during dialysis therapy, is currently the main cause of chronic liver disease in such population. The majority of patients acquired the disease through intravenous drug use or blood transfusion, with some risk factors identified. In this review we are dealing with the effect of renal transplantation on HCV infection and HCV-related complications after renal transplantation. Moreover, we are discussing the therapeutic options of HCV infection before and after renal transplantation, the best immunosuppressive protocol and lastly graft and patient survival in patients who underwent pretransplant management vs. those who were transplanted without treatment.http://dx.doi.org/10.4061/2011/471214
spellingShingle Osama Ashry Ahmed Gheith
Dilemma of HCV Infection in Renal Transplant Recipients
International Journal of Nephrology
title Dilemma of HCV Infection in Renal Transplant Recipients
title_full Dilemma of HCV Infection in Renal Transplant Recipients
title_fullStr Dilemma of HCV Infection in Renal Transplant Recipients
title_full_unstemmed Dilemma of HCV Infection in Renal Transplant Recipients
title_short Dilemma of HCV Infection in Renal Transplant Recipients
title_sort dilemma of hcv infection in renal transplant recipients
url http://dx.doi.org/10.4061/2011/471214
work_keys_str_mv AT osamaashryahmedgheith dilemmaofhcvinfectioninrenaltransplantrecipients