Surgical nonunion treatment of large-sized defects of femur and tibia based on the diamond concept

Aims: The aim of this study was to evaluate the radiological outcome of patients with large bone defects in the femur and tibia who were treated according to the guidelines of the diamond concept in our department (Centre for Orthopedics, Trauma Surgery, and Paraplegiology). Methods: The following...

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Main Authors: Sebastian Findeisen, Louis Mennerat, Thomas Ferbert, Lars Helbig, Tim N. Bewersdorf, Tobias Großner, Christian Schamberger, Gerhard Schmidmaier, Michael Tanner
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2025-01-01
Series:Bone & Joint Open
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Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2633-1462.61.BJO-2024-0096.R1
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author Sebastian Findeisen
Louis Mennerat
Thomas Ferbert
Lars Helbig
Tim N. Bewersdorf
Tobias Großner
Christian Schamberger
Gerhard Schmidmaier
Michael Tanner
author_facet Sebastian Findeisen
Louis Mennerat
Thomas Ferbert
Lars Helbig
Tim N. Bewersdorf
Tobias Großner
Christian Schamberger
Gerhard Schmidmaier
Michael Tanner
author_sort Sebastian Findeisen
collection DOAJ
description Aims: The aim of this study was to evaluate the radiological outcome of patients with large bone defects in the femur and tibia who were treated according to the guidelines of the diamond concept in our department (Centre for Orthopedics, Trauma Surgery, and Paraplegiology). Methods: The following retrospective, descriptive analysis consists of patients treated in our department between January 2010 and December 2021. In total, 628 patients were registered, of whom 108 presented with a large-sized defect (≥ 5 cm). A total of 70 patients met the inclusion criteria. The primary endpoint was radiological consolidation of nonunions after one and two years via a modified Lane-Sandhu Score, including only radiological parameters. Results: The mean defect size was 6.77 cm (SD 1.86), with the largest defect being 12.6 cm. Within two years after surgical treatment, 45 patients (64.3%) presented consolidation of the previous nonunion. After one year, six patients (8.6%) showed complete consolidation and 23 patients (32.9%) showed a considerable callus formation, whereas 41 patients (58.6%) showed a Lane-Sandhu score of 2 or below. Two years after surgery, 24 patients (34.3%) were categorized as Lane-Sandhu score 4, another 23 patients (32.9%) reached a score of 3, while 14 patients (20.0%) remained without final consolidation (score ≤ 2). A total of nine patients (12.9%) missed the two-year follow-up. The mean follow-up was 44.40 months (SD 32.00). The mean time period from nonunion surgery to consolidation was 16.42 months (SD 9.73) Conclusion: Patients with presentation of a large-sized nonunion require a structured and sufficiently long follow-up to secure the consolidation of the former nonunion. Furthermore, a follow-up of at least two years is required in order to declare a nonunion as consolidated, given that a significant part of the nonunions declared as not consolidated at one year showed consolidation within the second year. Moreover, the proven “gold standard” of a two-step procedure, so called Masquelet technique, shows effectiveness. Cite this article: Bone Jt Open 2024;6(1):26–34.
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spelling doaj-art-9bc59c5263914b43a383e11d2aea8d932025-01-28T05:38:53ZengThe British Editorial Society of Bone & Joint SurgeryBone & Joint Open2633-14622025-01-0161263410.1302/2633-1462.61.BJO-2024-0096.R1Surgical nonunion treatment of large-sized defects of femur and tibia based on the diamond conceptSebastian Findeisen0https://orcid.org/0000-0003-4083-1311Louis Mennerat1Thomas Ferbert2Lars Helbig3Tim N. Bewersdorf4https://orcid.org/0000-0002-1188-4791Tobias Großner5Christian Schamberger6Gerhard Schmidmaier7Michael Tanner8Clinic for Trauma and Reconstructive Surgery, Centre for Orthopedics, Trauma Surgery, and Paraplegiology, Heidelberg, GermanyClinic for Trauma and Reconstructive Surgery, Centre for Orthopedics, Trauma Surgery, and Paraplegiology, Heidelberg, GermanyClinic for Trauma and Reconstructive Surgery, Centre for Orthopedics, Trauma Surgery, and Paraplegiology, Heidelberg, GermanyClinic for Trauma and Reconstructive Surgery, Centre for Orthopedics, Trauma Surgery, and Paraplegiology, Heidelberg, GermanyClinic for Trauma and Reconstructive Surgery, Centre for Orthopedics, Trauma Surgery, and Paraplegiology, Heidelberg, GermanyClinic for Trauma and Reconstructive Surgery, Centre for Orthopedics, Trauma Surgery, and Paraplegiology, Heidelberg, GermanyClinic for Trauma and Reconstructive Surgery, Centre for Orthopedics, Trauma Surgery, and Paraplegiology, Heidelberg, GermanyClinic for Trauma and Reconstructive Surgery, Centre for Orthopedics, Trauma Surgery, and Paraplegiology, Heidelberg, GermanyClinic for Trauma and Reconstructive Surgery, Centre for Orthopedics, Trauma Surgery, and Paraplegiology, Heidelberg, GermanyAims: The aim of this study was to evaluate the radiological outcome of patients with large bone defects in the femur and tibia who were treated according to the guidelines of the diamond concept in our department (Centre for Orthopedics, Trauma Surgery, and Paraplegiology). Methods: The following retrospective, descriptive analysis consists of patients treated in our department between January 2010 and December 2021. In total, 628 patients were registered, of whom 108 presented with a large-sized defect (≥ 5 cm). A total of 70 patients met the inclusion criteria. The primary endpoint was radiological consolidation of nonunions after one and two years via a modified Lane-Sandhu Score, including only radiological parameters. Results: The mean defect size was 6.77 cm (SD 1.86), with the largest defect being 12.6 cm. Within two years after surgical treatment, 45 patients (64.3%) presented consolidation of the previous nonunion. After one year, six patients (8.6%) showed complete consolidation and 23 patients (32.9%) showed a considerable callus formation, whereas 41 patients (58.6%) showed a Lane-Sandhu score of 2 or below. Two years after surgery, 24 patients (34.3%) were categorized as Lane-Sandhu score 4, another 23 patients (32.9%) reached a score of 3, while 14 patients (20.0%) remained without final consolidation (score ≤ 2). A total of nine patients (12.9%) missed the two-year follow-up. The mean follow-up was 44.40 months (SD 32.00). The mean time period from nonunion surgery to consolidation was 16.42 months (SD 9.73) Conclusion: Patients with presentation of a large-sized nonunion require a structured and sufficiently long follow-up to secure the consolidation of the former nonunion. Furthermore, a follow-up of at least two years is required in order to declare a nonunion as consolidated, given that a significant part of the nonunions declared as not consolidated at one year showed consolidation within the second year. Moreover, the proven “gold standard” of a two-step procedure, so called Masquelet technique, shows effectiveness. Cite this article: Bone Jt Open 2024;6(1):26–34.https://online.boneandjoint.org.uk/doi/epdf/10.1302/2633-1462.61.BJO-2024-0096.R1nonunionnonunion therapysegmental bone defectmasquelet techniquediamond conceptfracture nonunionsfemurtibiasurgical treatmenttrauma surgerybone defectsradiological outcomecallus formationopen fractures
spellingShingle Sebastian Findeisen
Louis Mennerat
Thomas Ferbert
Lars Helbig
Tim N. Bewersdorf
Tobias Großner
Christian Schamberger
Gerhard Schmidmaier
Michael Tanner
Surgical nonunion treatment of large-sized defects of femur and tibia based on the diamond concept
Bone & Joint Open
nonunion
nonunion therapy
segmental bone defect
masquelet technique
diamond concept
fracture nonunions
femur
tibia
surgical treatment
trauma surgery
bone defects
radiological outcome
callus formation
open fractures
title Surgical nonunion treatment of large-sized defects of femur and tibia based on the diamond concept
title_full Surgical nonunion treatment of large-sized defects of femur and tibia based on the diamond concept
title_fullStr Surgical nonunion treatment of large-sized defects of femur and tibia based on the diamond concept
title_full_unstemmed Surgical nonunion treatment of large-sized defects of femur and tibia based on the diamond concept
title_short Surgical nonunion treatment of large-sized defects of femur and tibia based on the diamond concept
title_sort surgical nonunion treatment of large sized defects of femur and tibia based on the diamond concept
topic nonunion
nonunion therapy
segmental bone defect
masquelet technique
diamond concept
fracture nonunions
femur
tibia
surgical treatment
trauma surgery
bone defects
radiological outcome
callus formation
open fractures
url https://online.boneandjoint.org.uk/doi/epdf/10.1302/2633-1462.61.BJO-2024-0096.R1
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