From the mechanism of action to clinical management: A review of cardiovascular toxicity in adult treated with CAR-T therapy

From the mechanism of action to clinical management: A review of cardiovascular toxicity in adult treated with CAR-T therapy

Chimeric antigen receptor T-cell therapy represents an innovative approach to immunotherapy and currently stands out, particularly for oncohematological patients refractory to traditional treatments. Ongoing trials are further expanding its clinical use for new oncological and non-oncological indica...

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Main Authors: Frank Nunes, Breno Moreno de Gusmão, Franciely Bueno Wiginesk, Euler Manenti, Juliana Soares, Mizianne Garcia Freitas, Juliane Dantas Seabra-Garcez, Alexandre Manoel Varela, João Pedro Passos Dutra, Bruno Cesar Bacchiega, Tânia Félix Lorenzato da Fonseca Peixoto, Carolina Maria Pinto Domingues de Carvalho e Silva, Renato D. Lopes, Ariane Vieira Scarlatelli Macedo
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Hematology, Transfusion and Cell Therapy
Subjects:
Cardiotoxicity
Chimeric antigen receptor therapy
Cytokine release syndrome
Cardio-Oncology
Hematology
Online Access:http://www.sciencedirect.com/science/article/pii/S2531137924003195
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