Efficacy of Pomegranate Peel Extract Mouthwash on Gingivitis and C-reactive protein
Background and objective: Gingivitis is characterized as the world’s most predominant inflammatory periodontal disease. Healthy mouth and teeth are obtained by brushing and uses mouthwash. And because of the side effects of chlorhexidine, pomegranate peel extract mouthwash used alternative which ar...
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Kurdistan Higher Council Of Medical Specialties
2024-09-01
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| Series: | Advanced Medical Journal |
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| Online Access: | https://amj.khcms.edu.krd/index.php/main/article/view/487 |
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| author | Nabila Abdul Aziz Hussein Saeed Ali Mohammed |
| author_facet | Nabila Abdul Aziz Hussein Saeed Ali Mohammed |
| author_sort | Nabila Abdul Aziz Hussein |
| collection | DOAJ |
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Background and objective: Gingivitis is characterized as the world’s most predominant inflammatory periodontal disease. Healthy mouth and teeth are obtained by brushing and uses mouthwash. And because of the side effects of chlorhexidine, pomegranate peel extract mouthwash used alternative which are thought to have anti-inflammatory effect. The aim of this study is to prepare a herbal mouthwash and to evaluate the efficacy of pomegranate peel extract mouthwash on plaque index, gingival index, and C-reactive protein on moderate gingivitis patients.
Method: this study is a clinical crossover design study, which consists of 25 volunteers with moderate gingivitis, who visited Duhok Dental Training Center. This study started from December 2022 to March 2023. Plaque and gingival index with a sample of saliva for C-reactive protein measuring were taken as a baseline before each mouth wash and after that, the pomegranate peel extract mouthwash was used for two weeks, then three weeks wash out between them, then chlorhexidine mouth wash was used for two weeks (crossover method). All saliva samples were analyzed using (CRP ELISA Test).
Results: Twenty-five patients who used pomegranate peel extract mouthwash showed a significant reduction after two weeks used (CRP=162.28, GI=0.54, PI=0.82) and p value (<0.0001) in mean C-reactive protein, gingival index, and plaque index from baseline which was (CRP=669.78, GI=1.88, PI=2.11).
Conclusion: Pomegranate peel extract mouthwash had been shown effective against moderate gingivitis in adult patients with no systemic diseases through lowering in mean salivary C-reactive protein, gingival index, and plaque index.
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| format | Article |
| id | doaj-art-9bba3d4561824b3792c9b975b0e2b545 |
| institution | OA Journals |
| issn | 2958-8979 2957-3580 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Kurdistan Higher Council Of Medical Specialties |
| record_format | Article |
| series | Advanced Medical Journal |
| spelling | doaj-art-9bba3d4561824b3792c9b975b0e2b5452025-08-20T02:27:24ZengKurdistan Higher Council Of Medical SpecialtiesAdvanced Medical Journal2958-89792957-35802024-09-019310.56056/amj.2024.284488Efficacy of Pomegranate Peel Extract Mouthwash on Gingivitis and C-reactive proteinNabila Abdul Aziz Hussein0Saeed Ali Mohammed1Kurdistan Higher Council of Medical Candidate, Duhok Training CenterAssistant Prof, Department of Periodontics, College of Dentistry, Duhok University Iraq Background and objective: Gingivitis is characterized as the world’s most predominant inflammatory periodontal disease. Healthy mouth and teeth are obtained by brushing and uses mouthwash. And because of the side effects of chlorhexidine, pomegranate peel extract mouthwash used alternative which are thought to have anti-inflammatory effect. The aim of this study is to prepare a herbal mouthwash and to evaluate the efficacy of pomegranate peel extract mouthwash on plaque index, gingival index, and C-reactive protein on moderate gingivitis patients. Method: this study is a clinical crossover design study, which consists of 25 volunteers with moderate gingivitis, who visited Duhok Dental Training Center. This study started from December 2022 to March 2023. Plaque and gingival index with a sample of saliva for C-reactive protein measuring were taken as a baseline before each mouth wash and after that, the pomegranate peel extract mouthwash was used for two weeks, then three weeks wash out between them, then chlorhexidine mouth wash was used for two weeks (crossover method). All saliva samples were analyzed using (CRP ELISA Test). Results: Twenty-five patients who used pomegranate peel extract mouthwash showed a significant reduction after two weeks used (CRP=162.28, GI=0.54, PI=0.82) and p value (<0.0001) in mean C-reactive protein, gingival index, and plaque index from baseline which was (CRP=669.78, GI=1.88, PI=2.11). Conclusion: Pomegranate peel extract mouthwash had been shown effective against moderate gingivitis in adult patients with no systemic diseases through lowering in mean salivary C-reactive protein, gingival index, and plaque index. https://amj.khcms.edu.krd/index.php/main/article/view/487ChlorhexidineC-Reactive proteinGingivitisPomegranatesaliva |
| spellingShingle | Nabila Abdul Aziz Hussein Saeed Ali Mohammed Efficacy of Pomegranate Peel Extract Mouthwash on Gingivitis and C-reactive protein Advanced Medical Journal Chlorhexidine C-Reactive protein Gingivitis Pomegranate saliva |
| title | Efficacy of Pomegranate Peel Extract Mouthwash on Gingivitis and C-reactive protein |
| title_full | Efficacy of Pomegranate Peel Extract Mouthwash on Gingivitis and C-reactive protein |
| title_fullStr | Efficacy of Pomegranate Peel Extract Mouthwash on Gingivitis and C-reactive protein |
| title_full_unstemmed | Efficacy of Pomegranate Peel Extract Mouthwash on Gingivitis and C-reactive protein |
| title_short | Efficacy of Pomegranate Peel Extract Mouthwash on Gingivitis and C-reactive protein |
| title_sort | efficacy of pomegranate peel extract mouthwash on gingivitis and c reactive protein |
| topic | Chlorhexidine C-Reactive protein Gingivitis Pomegranate saliva |
| url | https://amj.khcms.edu.krd/index.php/main/article/view/487 |
| work_keys_str_mv | AT nabilaabdulazizhussein efficacyofpomegranatepeelextractmouthwashongingivitisandcreactiveprotein AT saeedalimohammed efficacyofpomegranatepeelextractmouthwashongingivitisandcreactiveprotein |