Review on 3D Printing Filaments Used in Fused Deposition Modeling Method for Dermatological Preparations
Three-dimensional printing, particularly Fused Deposition Modeling (FDM), has revolutionized dermatological drug delivery by offering the ability to create personalized and precise drug formulations. This technology enables the design of customized drug delivery systems using a variety of polymers,...
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| Format: | Article |
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MDPI AG
2025-05-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/30/11/2411 |
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| author | Yong Li Chan Riyanto Teguh Widodo Long Chiau Ming Abdullah Khan Syed Atif Abbas Ng Yen Ping Zarif Mohamed Sofian Mahibub Mahamadsa Kanakal |
| author_facet | Yong Li Chan Riyanto Teguh Widodo Long Chiau Ming Abdullah Khan Syed Atif Abbas Ng Yen Ping Zarif Mohamed Sofian Mahibub Mahamadsa Kanakal |
| author_sort | Yong Li Chan |
| collection | DOAJ |
| description | Three-dimensional printing, particularly Fused Deposition Modeling (FDM), has revolutionized dermatological drug delivery by offering the ability to create personalized and precise drug formulations. This technology enables the design of customized drug delivery systems using a variety of polymers, such as Polylactic Acid (PLA), Polyvinyl Alcohol (PVA), Polyethylene Glycol (PEG), and Polycaprolactone (PCL), each with unique properties that enhance drug release, patient compliance, and treatment efficacy. This review analyzes these polymers in terms of their advantages, limitations, and suitability for dermatological applications. The ability to tailor these materials offers significant potential in overcoming treatment regimens. Additionally, the customization of three-dimensional-printed drug delivery systems provides a platform for creating patient-specific solutions that are more effective and adaptable to individual needs. Despite challenges such as moisture sensitivity and mechanical brittleness, the potential of FDM technology to improve dermatological treatments remains promising. The future of three-dimensional printing in dermatology lies in the integration of optimized materials and advanced printing techniques, which could further enhance patient-specific care and broaden the clinical applicability of these technologies in the pharmaceutical and biomedical sectors. By addressing these limitations and expanding material choices, FDM-based drug delivery systems have the potential to revolutionize the management of dermatological conditions, offering improved therapeutic outcomes and quality of life for patients. |
| format | Article |
| id | doaj-art-9bb8b1f392ee4cddb05dcdabdd6fd7dd |
| institution | OA Journals |
| issn | 1420-3049 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj-art-9bb8b1f392ee4cddb05dcdabdd6fd7dd2025-08-20T02:32:52ZengMDPI AGMolecules1420-30492025-05-013011241110.3390/molecules30112411Review on 3D Printing Filaments Used in Fused Deposition Modeling Method for Dermatological PreparationsYong Li Chan0Riyanto Teguh Widodo1Long Chiau Ming2Abdullah Khan3Syed Atif Abbas4Ng Yen Ping5Zarif Mohamed Sofian6Mahibub Mahamadsa Kanakal7Department of Pharmaceutical Technology, Faculty of Pharmacy, Universiti Malaya, Kuala Lumpur 50603, MalaysiaDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Universiti Malaya, Kuala Lumpur 50603, MalaysiaDatta Meghe College of Pharmacy, Datta Meghe Institute of Higher Education (Deemed to be University), Sawangi (M), Wardha 442004, IndiaFaculty of Pharmacy, Quest International University, Ipoh 30250, MalaysiaFaculty of Pharmacy, Quest International University, Ipoh 30250, MalaysiaFaculty of Pharmacy, Quest International University, Ipoh 30250, MalaysiaDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Universiti Malaya, Kuala Lumpur 50603, MalaysiaFaculty of Pharmacy, Quest International University, Ipoh 30250, MalaysiaThree-dimensional printing, particularly Fused Deposition Modeling (FDM), has revolutionized dermatological drug delivery by offering the ability to create personalized and precise drug formulations. This technology enables the design of customized drug delivery systems using a variety of polymers, such as Polylactic Acid (PLA), Polyvinyl Alcohol (PVA), Polyethylene Glycol (PEG), and Polycaprolactone (PCL), each with unique properties that enhance drug release, patient compliance, and treatment efficacy. This review analyzes these polymers in terms of their advantages, limitations, and suitability for dermatological applications. The ability to tailor these materials offers significant potential in overcoming treatment regimens. Additionally, the customization of three-dimensional-printed drug delivery systems provides a platform for creating patient-specific solutions that are more effective and adaptable to individual needs. Despite challenges such as moisture sensitivity and mechanical brittleness, the potential of FDM technology to improve dermatological treatments remains promising. The future of three-dimensional printing in dermatology lies in the integration of optimized materials and advanced printing techniques, which could further enhance patient-specific care and broaden the clinical applicability of these technologies in the pharmaceutical and biomedical sectors. By addressing these limitations and expanding material choices, FDM-based drug delivery systems have the potential to revolutionize the management of dermatological conditions, offering improved therapeutic outcomes and quality of life for patients.https://www.mdpi.com/1420-3049/30/11/2411polymersfilaments3D printingfused deposition modeling (FDM)dermatology preparationstopical |
| spellingShingle | Yong Li Chan Riyanto Teguh Widodo Long Chiau Ming Abdullah Khan Syed Atif Abbas Ng Yen Ping Zarif Mohamed Sofian Mahibub Mahamadsa Kanakal Review on 3D Printing Filaments Used in Fused Deposition Modeling Method for Dermatological Preparations Molecules polymers filaments 3D printing fused deposition modeling (FDM) dermatology preparations topical |
| title | Review on 3D Printing Filaments Used in Fused Deposition Modeling Method for Dermatological Preparations |
| title_full | Review on 3D Printing Filaments Used in Fused Deposition Modeling Method for Dermatological Preparations |
| title_fullStr | Review on 3D Printing Filaments Used in Fused Deposition Modeling Method for Dermatological Preparations |
| title_full_unstemmed | Review on 3D Printing Filaments Used in Fused Deposition Modeling Method for Dermatological Preparations |
| title_short | Review on 3D Printing Filaments Used in Fused Deposition Modeling Method for Dermatological Preparations |
| title_sort | review on 3d printing filaments used in fused deposition modeling method for dermatological preparations |
| topic | polymers filaments 3D printing fused deposition modeling (FDM) dermatology preparations topical |
| url | https://www.mdpi.com/1420-3049/30/11/2411 |
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