Immune subversion by Mycobacterium tuberculosis through CCR5 mediated signaling: involvement of IL-10.

Immune subversion by Mycobacterium tuberculosis through CCR5 mediated signaling: involvement of IL-10.

Tuberculosis is characterized by severe immunosuppression of the host macrophages, resulting in the loss of the host protective immune responses. During Mycobacterium tuberculosis infection, the pathogen modulates C-C Chemokine Receptor 5 (CCR5) to enhance IL-10 production, indicating the possible i...

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Main Authors: Shibali Das, Sayantan Banerjee, Saikat Majumder, Bidisha Paul Chowdhury, Avranil Goswami, Kuntal Halder, Urmita Chakraborty, Nishith K Pal, Subrata Majumdar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0092477&type=printable
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