Personality traits and their effects in patients with hemifacial spasm

Abstract This study aimed to investigate the personality traits of patients with hemifacial spasm (HFS) and their effects on depression, anxiety, social phobia, and quality of life (QoL). This was a prospective cross-sectional study. Fifty patients diagnosed with HFS and 50 age-, sex-, and education...

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Main Authors: Jeong-A Lee, Yun Kyung Han, Won Je Jung, Byung H. Lee, Seunghoon Lee
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-97368-7
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author Jeong-A Lee
Yun Kyung Han
Won Je Jung
Byung H. Lee
Seunghoon Lee
author_facet Jeong-A Lee
Yun Kyung Han
Won Je Jung
Byung H. Lee
Seunghoon Lee
author_sort Jeong-A Lee
collection DOAJ
description Abstract This study aimed to investigate the personality traits of patients with hemifacial spasm (HFS) and their effects on depression, anxiety, social phobia, and quality of life (QoL). This was a prospective cross-sectional study. Fifty patients diagnosed with HFS and 50 age-, sex-, and education-matched healthy controls (HCs) were enrolled between June and September 2023. Personality traits were assessed using the Korean version of the 50-item International Personality Item Pool (IPIP) representation of Goldberg markers for the Big-Five factor structure. In terms of personality traits, patients with HFS showed lower extraversion and higher neuroticism than HCs. HFS patients also had higher levels of depression, anxiety, and social phobia, as well as lower QoL, than HCs. In patients with HFS, neuroticism decreased with age and was higher in patients with less severe spasms compared to patients with the most severe spasms. Higher extraversion was associated with lower depression and social phobia, and higher QoL. Higher neuroticism was associated with higher depression, anxiety, social interaction anxiety and social phobia, and lower QoL. Understanding these results will not only be helpful in understanding the disease and patients, but it could also be used to establish personalized management strategies.
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spelling doaj-art-9ba9f99056bf433fa7979dc42ba9035e2025-08-20T03:26:42ZengNature PortfolioScientific Reports2045-23222025-04-011511910.1038/s41598-025-97368-7Personality traits and their effects in patients with hemifacial spasmJeong-A Lee0Yun Kyung Han1Won Je Jung2Byung H. Lee3Seunghoon Lee4Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Nursing, Samsung Medical CenterDepartment of Nursing, Samsung Medical CenterDepartment of Neurology, Samsung Medical CenterDepartment of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of MedicineAbstract This study aimed to investigate the personality traits of patients with hemifacial spasm (HFS) and their effects on depression, anxiety, social phobia, and quality of life (QoL). This was a prospective cross-sectional study. Fifty patients diagnosed with HFS and 50 age-, sex-, and education-matched healthy controls (HCs) were enrolled between June and September 2023. Personality traits were assessed using the Korean version of the 50-item International Personality Item Pool (IPIP) representation of Goldberg markers for the Big-Five factor structure. In terms of personality traits, patients with HFS showed lower extraversion and higher neuroticism than HCs. HFS patients also had higher levels of depression, anxiety, and social phobia, as well as lower QoL, than HCs. In patients with HFS, neuroticism decreased with age and was higher in patients with less severe spasms compared to patients with the most severe spasms. Higher extraversion was associated with lower depression and social phobia, and higher QoL. Higher neuroticism was associated with higher depression, anxiety, social interaction anxiety and social phobia, and lower QoL. Understanding these results will not only be helpful in understanding the disease and patients, but it could also be used to establish personalized management strategies.https://doi.org/10.1038/s41598-025-97368-7AnxietyDepressionHemifacial spasmPersonalityQuality of lifeSocial phobia
spellingShingle Jeong-A Lee
Yun Kyung Han
Won Je Jung
Byung H. Lee
Seunghoon Lee
Personality traits and their effects in patients with hemifacial spasm
Scientific Reports
Anxiety
Depression
Hemifacial spasm
Personality
Quality of life
Social phobia
title Personality traits and their effects in patients with hemifacial spasm
title_full Personality traits and their effects in patients with hemifacial spasm
title_fullStr Personality traits and their effects in patients with hemifacial spasm
title_full_unstemmed Personality traits and their effects in patients with hemifacial spasm
title_short Personality traits and their effects in patients with hemifacial spasm
title_sort personality traits and their effects in patients with hemifacial spasm
topic Anxiety
Depression
Hemifacial spasm
Personality
Quality of life
Social phobia
url https://doi.org/10.1038/s41598-025-97368-7
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