Spontaneous Pneumothorax Secondary to Lymphangioleiomyomatosis
Lymphangioleiomyomatosis (LAM) is a rare cystic lung disease presenting primarily in women of child-bearing age. It can occur sporadically or in association with tuberous sclerosis. Here, we discuss the case of a 29-year-old woman on oral contraceptive pills (OCPs) for years, who presented with sudd...
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| Format: | Article |
| Language: | English |
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American College of Physicians
2025-06-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2024.1009 |
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| _version_ | 1849689547782225920 |
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| author | Franshisca Hayek Leonel Al Dakar Liam Coyne Rupali Sood Michelle Sharp |
| author_facet | Franshisca Hayek Leonel Al Dakar Liam Coyne Rupali Sood Michelle Sharp |
| author_sort | Franshisca Hayek |
| collection | DOAJ |
| description | Lymphangioleiomyomatosis (LAM) is a rare cystic lung disease presenting primarily in women of child-bearing age. It can occur sporadically or in association with tuberous sclerosis. Here, we discuss the case of a 29-year-old woman on oral contraceptive pills (OCPs) for years, who presented with sudden-onset chest pain and dyspnea found to have a pneumothorax. Serologic testing confirmed a diagnosis of LAM. An early diagnosis can lead to earlier treatment with sirolimus, which can improve lung function and survival among those with LAM. |
| format | Article |
| id | doaj-art-9b98309cc4294b7fa77b7044afd47d2b |
| institution | DOAJ |
| issn | 2767-7664 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | American College of Physicians |
| record_format | Article |
| series | Annals of Internal Medicine: Clinical Cases |
| spelling | doaj-art-9b98309cc4294b7fa77b7044afd47d2b2025-08-20T03:21:34ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642025-06-014610.7326/aimcc.2024.1009Spontaneous Pneumothorax Secondary to LymphangioleiomyomatosisFranshisca Hayek0Leonel Al Dakar1Liam Coyne2Rupali Sood3Michelle Sharp41Johns Hopkins University School of Medicine, Baltimore, Maryland1Johns Hopkins University School of Medicine, Baltimore, Maryland2Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland2Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland2Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MarylandLymphangioleiomyomatosis (LAM) is a rare cystic lung disease presenting primarily in women of child-bearing age. It can occur sporadically or in association with tuberous sclerosis. Here, we discuss the case of a 29-year-old woman on oral contraceptive pills (OCPs) for years, who presented with sudden-onset chest pain and dyspnea found to have a pneumothorax. Serologic testing confirmed a diagnosis of LAM. An early diagnosis can lead to earlier treatment with sirolimus, which can improve lung function and survival among those with LAM.https://www.acpjournals.org/doi/10.7326/aimcc.2024.1009 |
| spellingShingle | Franshisca Hayek Leonel Al Dakar Liam Coyne Rupali Sood Michelle Sharp Spontaneous Pneumothorax Secondary to Lymphangioleiomyomatosis Annals of Internal Medicine: Clinical Cases |
| title | Spontaneous Pneumothorax Secondary to Lymphangioleiomyomatosis |
| title_full | Spontaneous Pneumothorax Secondary to Lymphangioleiomyomatosis |
| title_fullStr | Spontaneous Pneumothorax Secondary to Lymphangioleiomyomatosis |
| title_full_unstemmed | Spontaneous Pneumothorax Secondary to Lymphangioleiomyomatosis |
| title_short | Spontaneous Pneumothorax Secondary to Lymphangioleiomyomatosis |
| title_sort | spontaneous pneumothorax secondary to lymphangioleiomyomatosis |
| url | https://www.acpjournals.org/doi/10.7326/aimcc.2024.1009 |
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