Developmental Coordination Disorder: Is Clumsy Motor Behavior Caused by a Lesion of the Brain at Early Age?
Children presenting with Developmental Coordination Disorder or clumsiness often exhibit signs of minor neurological dysfunction (MND). The data of the Groningen Perinatal Project, a long-term follow-up project .on the relations between prenatal and perinatal adversities and neurological, behavioral...
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| Format: | Article |
| Language: | English |
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Wiley
2003-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/NP.2003.39 |
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| _version_ | 1850179645671997440 |
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| author | Mijna Hadders-Algra |
| author_facet | Mijna Hadders-Algra |
| author_sort | Mijna Hadders-Algra |
| collection | DOAJ |
| description | Children presenting with Developmental
Coordination Disorder or clumsiness often
exhibit signs of minor neurological dysfunction
(MND). The data of the Groningen Perinatal
Project, a long-term follow-up project .on the
relations between prenatal and perinatal
adversities and neurological, behavioral, and
cognitive development revealed that two basic
forms of MND can be distinguished: simple and
complex MND. During school age children with
simple MND are characterized by the presence
of one or two dysfunctional clusters of MND, in
adolescence by the presence of choreiform
dyskinesia or hypotonia. Probably the major
sources of origin of simple MND are genetic
constitution and stress during early life. Simple
MND might reflect the lower tail of the normal
distribution of the quality of non-pathological
brain function. In line with this hypothesis is
the finding that simple MND is associated with
only a moderately increased risk for learning and
behavioral problems. Children with
complex MND present at school age with at
least three dysfunctional clusters of MND, in
adolescence with problems in fine manipulation
or coordination. Perinatal adversities play an
evident etiological role in the development of
complex MND, suggesting that it might be
attributed to a lesion of the brain at early age.
In line with this idea is the finding that complex
MND shows .a strong correlation with attention
and learning problems. |
| format | Article |
| id | doaj-art-9b975e8fcf0f4096b78e5c23d7a67f23 |
| institution | OA Journals |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2003-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-9b975e8fcf0f4096b78e5c23d7a67f232025-08-20T02:18:27ZengWileyNeural Plasticity2090-59041687-54432003-01-01101-2395010.1155/NP.2003.39Developmental Coordination Disorder: Is Clumsy Motor Behavior Caused by a Lesion of the Brain at Early Age?Mijna Hadders-Algra0Department of Neurology Developmental Neurology, University of Groningen, Hanzeplein 1, Groningen 9713 GZ, The NetherlandsChildren presenting with Developmental Coordination Disorder or clumsiness often exhibit signs of minor neurological dysfunction (MND). The data of the Groningen Perinatal Project, a long-term follow-up project .on the relations between prenatal and perinatal adversities and neurological, behavioral, and cognitive development revealed that two basic forms of MND can be distinguished: simple and complex MND. During school age children with simple MND are characterized by the presence of one or two dysfunctional clusters of MND, in adolescence by the presence of choreiform dyskinesia or hypotonia. Probably the major sources of origin of simple MND are genetic constitution and stress during early life. Simple MND might reflect the lower tail of the normal distribution of the quality of non-pathological brain function. In line with this hypothesis is the finding that simple MND is associated with only a moderately increased risk for learning and behavioral problems. Children with complex MND present at school age with at least three dysfunctional clusters of MND, in adolescence with problems in fine manipulation or coordination. Perinatal adversities play an evident etiological role in the development of complex MND, suggesting that it might be attributed to a lesion of the brain at early age. In line with this idea is the finding that complex MND shows .a strong correlation with attention and learning problems.http://dx.doi.org/10.1155/NP.2003.39 |
| spellingShingle | Mijna Hadders-Algra Developmental Coordination Disorder: Is Clumsy Motor Behavior Caused by a Lesion of the Brain at Early Age? Neural Plasticity |
| title | Developmental Coordination Disorder: Is Clumsy Motor Behavior Caused by a Lesion of the Brain at Early Age? |
| title_full | Developmental Coordination Disorder: Is Clumsy Motor Behavior Caused by a Lesion of the Brain at Early Age? |
| title_fullStr | Developmental Coordination Disorder: Is Clumsy Motor Behavior Caused by a Lesion of the Brain at Early Age? |
| title_full_unstemmed | Developmental Coordination Disorder: Is Clumsy Motor Behavior Caused by a Lesion of the Brain at Early Age? |
| title_short | Developmental Coordination Disorder: Is Clumsy Motor Behavior Caused by a Lesion of the Brain at Early Age? |
| title_sort | developmental coordination disorder is clumsy motor behavior caused by a lesion of the brain at early age |
| url | http://dx.doi.org/10.1155/NP.2003.39 |
| work_keys_str_mv | AT mijnahaddersalgra developmentalcoordinationdisorderisclumsymotorbehaviorcausedbyalesionofthebrainatearlyage |