The Role of Vaccination in the Control of SARS
We assess pre-outbreak and during-outbreak vaccination as control strategies for SARS epidemics using a mathematical model that includes susceptible, latent (traced and untraced), infectious, isolated and recovered individuals. Scenarios focusing on policies that include contact tracing and levels o...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
AIMS Press
2005-09-01
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| Series: | Mathematical Biosciences and Engineering |
| Subjects: | |
| Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2005.2.753 |
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| _version_ | 1832590272645562368 |
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| author | Julijana Gjorgjieva Kelly Smith Gerardo Chowell Fabio Sánchez Jessica Snyder Carlos Castillo-Chavez |
| author_facet | Julijana Gjorgjieva Kelly Smith Gerardo Chowell Fabio Sánchez Jessica Snyder Carlos Castillo-Chavez |
| author_sort | Julijana Gjorgjieva |
| collection | DOAJ |
| description | We assess pre-outbreak and during-outbreak vaccination as control strategies for SARS epidemics using a mathematical model that includes susceptible, latent (traced and untraced), infectious, isolated and recovered individuals. Scenarios focusing on policies that include contact tracing and levels of self-isolation among untraced infected individuals are explored. Bounds on the proportion of pre-outbreak successfully vaccinated individuals are provided using the the basic reproductive number. Uncertainty and sensitivity analyses on the reproductive number are carried out. The final epidemic size under different vaccination scenarios is computed. |
| format | Article |
| id | doaj-art-9b8792af125844ce905bd98632ada948 |
| institution | Kabale University |
| issn | 1551-0018 |
| language | English |
| publishDate | 2005-09-01 |
| publisher | AIMS Press |
| record_format | Article |
| series | Mathematical Biosciences and Engineering |
| spelling | doaj-art-9b8792af125844ce905bd98632ada9482025-01-24T01:49:46ZengAIMS PressMathematical Biosciences and Engineering1551-00182005-09-012475376910.3934/mbe.2005.2.753The Role of Vaccination in the Control of SARSJulijana Gjorgjieva0Kelly Smith1Gerardo Chowell2Fabio Sánchez3Jessica Snyder4Carlos Castillo-Chavez5Department of Mathematics, Harvey Mudd College, 340 E. Foothill Blvd. Claremont, CA 91711Mathematics department, Clarion University of Pennsylvania, Clarion, Pennsylvania 16214Theoretical Division (MS B284), Los Alamos National Laboratory, Los Alamos, NM 87545BSCB, Cornell University, Ithaca, NY 14853College of Sciences, Georgia Institute of Technology, Atlanta, Georgia 30332Department of Mathematics & Statistics, Arizona State University, Tempe, AZ 85287-1804We assess pre-outbreak and during-outbreak vaccination as control strategies for SARS epidemics using a mathematical model that includes susceptible, latent (traced and untraced), infectious, isolated and recovered individuals. Scenarios focusing on policies that include contact tracing and levels of self-isolation among untraced infected individuals are explored. Bounds on the proportion of pre-outbreak successfully vaccinated individuals are provided using the the basic reproductive number. Uncertainty and sensitivity analyses on the reproductive number are carried out. The final epidemic size under different vaccination scenarios is computed.https://www.aimspress.com/article/doi/10.3934/mbe.2005.2.753vaccinationisolation.severe acute respiratory syndrome (sars)contact tracingmathematical model |
| spellingShingle | Julijana Gjorgjieva Kelly Smith Gerardo Chowell Fabio Sánchez Jessica Snyder Carlos Castillo-Chavez The Role of Vaccination in the Control of SARS Mathematical Biosciences and Engineering vaccination isolation. severe acute respiratory syndrome (sars) contact tracing mathematical model |
| title | The Role of Vaccination in the Control of SARS |
| title_full | The Role of Vaccination in the Control of SARS |
| title_fullStr | The Role of Vaccination in the Control of SARS |
| title_full_unstemmed | The Role of Vaccination in the Control of SARS |
| title_short | The Role of Vaccination in the Control of SARS |
| title_sort | role of vaccination in the control of sars |
| topic | vaccination isolation. severe acute respiratory syndrome (sars) contact tracing mathematical model |
| url | https://www.aimspress.com/article/doi/10.3934/mbe.2005.2.753 |
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