Temporal profiling of M‐TEER‐related complications

Abstract Aims Transcatheter edge‐to‐edge repair of the mitral valve (M‐TEER) is known for its low complication rates. However, the optimal level and duration of post‐procedural care remain unclear. This study aimed to identify the specific timeframe of post‐procedural complications following M‐TEER....

Full description

Saved in:
Bibliographic Details
Main Authors: Jafer Haschemi, Hanna Schrameck, Jean Marc Haurand, Daniel Oehler, Maximilian Spieker, Fabian Voss, Malte Kelm, Amin Polzin, Patrick Horn
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:ESC Heart Failure
Subjects:
Online Access:https://doi.org/10.1002/ehf2.15220
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850191974130253824
author Jafer Haschemi
Hanna Schrameck
Jean Marc Haurand
Daniel Oehler
Maximilian Spieker
Fabian Voss
Malte Kelm
Amin Polzin
Patrick Horn
author_facet Jafer Haschemi
Hanna Schrameck
Jean Marc Haurand
Daniel Oehler
Maximilian Spieker
Fabian Voss
Malte Kelm
Amin Polzin
Patrick Horn
author_sort Jafer Haschemi
collection DOAJ
description Abstract Aims Transcatheter edge‐to‐edge repair of the mitral valve (M‐TEER) is known for its low complication rates. However, the optimal level and duration of post‐procedural care remain unclear. This study aimed to identify the specific timeframe of post‐procedural complications following M‐TEER. Methods and results We conducted a retrospective analysis of 865 patients who underwent M‐TEER at the University Hospital Düsseldorf between August 2010 and August 2023. Our analysis focused on a comprehensive examination of all acute post‐procedural complications (1–100 h), considering the time point of occurrence or diagnosis. The complication analysed included cardiogenic shock, pericardial tamponade, stroke, cardiac arrhythmias, bleeding, acute kidney injury, myocardial infarction, peripheral vascular ischaemia and in‐hospital mortality. Results The median age was 80 (74, 84) years, and the EuroScore II was high (6.5 [4.0, 12.0] %). Functional mitral regurgitation (MR) was more common than degenerative or mixed MR (69% vs. 20%. respectively; 11%). Technical success rate was 97.2%. Overall, acute post‐procedural complications occurred in 87 patients (10.1%). Most complications (75.9%) occurred within the first 4 h post‐procedure. 12.6% of the complications occurred during the period between 4 and 24 h post‐procedure, and 11.5% of the complications happened between 24 and 100 h post‐procedure. Life‐threatening complications were observed only within the first 4 h post‐procedure. Conclusions The majority of post‐procedural complications after M‐TEER occur within the first 4 h, with pericardial tamponade and major bleeding occurring only during this period. These findings provide valuable insight for physicians in determining the optimal surveillance and monitoring duration after M‐TEER within clinical settings.
format Article
id doaj-art-9b819f6eaee042a8b10e77951d03d333
institution OA Journals
issn 2055-5822
language English
publishDate 2025-06-01
publisher Wiley
record_format Article
series ESC Heart Failure
spelling doaj-art-9b819f6eaee042a8b10e77951d03d3332025-08-20T02:14:43ZengWileyESC Heart Failure2055-58222025-06-011232107211210.1002/ehf2.15220Temporal profiling of M‐TEER‐related complicationsJafer Haschemi0Hanna Schrameck1Jean Marc Haurand2Daniel Oehler3Maximilian Spieker4Fabian Voss5Malte Kelm6Amin Polzin7Patrick Horn8Division of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty University of Düsseldorf Düsseldorf GermanyDivision of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty University of Düsseldorf Düsseldorf GermanyDivision of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty University of Düsseldorf Düsseldorf GermanyDivision of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty University of Düsseldorf Düsseldorf GermanyDivision of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty University of Düsseldorf Düsseldorf GermanyDivision of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty University of Düsseldorf Düsseldorf GermanyDivision of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty University of Düsseldorf Düsseldorf GermanyDivision of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty University of Düsseldorf Düsseldorf GermanyDivision of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty University of Düsseldorf Düsseldorf GermanyAbstract Aims Transcatheter edge‐to‐edge repair of the mitral valve (M‐TEER) is known for its low complication rates. However, the optimal level and duration of post‐procedural care remain unclear. This study aimed to identify the specific timeframe of post‐procedural complications following M‐TEER. Methods and results We conducted a retrospective analysis of 865 patients who underwent M‐TEER at the University Hospital Düsseldorf between August 2010 and August 2023. Our analysis focused on a comprehensive examination of all acute post‐procedural complications (1–100 h), considering the time point of occurrence or diagnosis. The complication analysed included cardiogenic shock, pericardial tamponade, stroke, cardiac arrhythmias, bleeding, acute kidney injury, myocardial infarction, peripheral vascular ischaemia and in‐hospital mortality. Results The median age was 80 (74, 84) years, and the EuroScore II was high (6.5 [4.0, 12.0] %). Functional mitral regurgitation (MR) was more common than degenerative or mixed MR (69% vs. 20%. respectively; 11%). Technical success rate was 97.2%. Overall, acute post‐procedural complications occurred in 87 patients (10.1%). Most complications (75.9%) occurred within the first 4 h post‐procedure. 12.6% of the complications occurred during the period between 4 and 24 h post‐procedure, and 11.5% of the complications happened between 24 and 100 h post‐procedure. Life‐threatening complications were observed only within the first 4 h post‐procedure. Conclusions The majority of post‐procedural complications after M‐TEER occur within the first 4 h, with pericardial tamponade and major bleeding occurring only during this period. These findings provide valuable insight for physicians in determining the optimal surveillance and monitoring duration after M‐TEER within clinical settings.https://doi.org/10.1002/ehf2.15220Mitral regurgitationMitraClipPascalSafetyEvents
spellingShingle Jafer Haschemi
Hanna Schrameck
Jean Marc Haurand
Daniel Oehler
Maximilian Spieker
Fabian Voss
Malte Kelm
Amin Polzin
Patrick Horn
Temporal profiling of M‐TEER‐related complications
ESC Heart Failure
Mitral regurgitation
MitraClip
Pascal
Safety
Events
title Temporal profiling of M‐TEER‐related complications
title_full Temporal profiling of M‐TEER‐related complications
title_fullStr Temporal profiling of M‐TEER‐related complications
title_full_unstemmed Temporal profiling of M‐TEER‐related complications
title_short Temporal profiling of M‐TEER‐related complications
title_sort temporal profiling of m teer related complications
topic Mitral regurgitation
MitraClip
Pascal
Safety
Events
url https://doi.org/10.1002/ehf2.15220
work_keys_str_mv AT jaferhaschemi temporalprofilingofmteerrelatedcomplications
AT hannaschrameck temporalprofilingofmteerrelatedcomplications
AT jeanmarchaurand temporalprofilingofmteerrelatedcomplications
AT danieloehler temporalprofilingofmteerrelatedcomplications
AT maximilianspieker temporalprofilingofmteerrelatedcomplications
AT fabianvoss temporalprofilingofmteerrelatedcomplications
AT maltekelm temporalprofilingofmteerrelatedcomplications
AT aminpolzin temporalprofilingofmteerrelatedcomplications
AT patrickhorn temporalprofilingofmteerrelatedcomplications