PET Imaging Expedites Detection of Aberration in the Humanization of an Annexin A1 Targeting Antibody

PET Imaging Expedites Detection of Aberration in the Humanization of an Annexin A1 Targeting Antibody

<b>Objectives</b>: Annexin-A1 is a 37 kDa phospholipid-binding protein which is concentrated in a truncated 34 kDa form (AnnA1) in caveolae on the tumor vascular endothelial cell surface with expression in many tumor types. PRISM developed the monoclonal mouse antibody mAnnA1 against Ann...

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Bibliographic Details
Main Authors: Hailey A. Houson, Brian D. Wright, Solana R. Fernandez, Tim Buss, Sharon L. White, Brittany Cederstrom, James M. Omweri, Jonathan E. McConathy, Jan E. Schnitzer, Suzanne E. Lapi
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Pharmaceuticals
Subjects:
zirconium-89
antibody imaging
dosimetry
translation
Online Access:https://www.mdpi.com/1424-8247/18/3/295
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