Muscle-Restricted Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 Knockout Partially Corrects Muscle Contractility After Spinal Cord Injury in Mice

Muscle-Restricted Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 Knockout Partially Corrects Muscle Contractility After Spinal Cord Injury in Mice

Spinal cord injury (SCI) results in severe atrophy of skeletal muscle in paralyzed regions, and a decrease in the force generated by muscle per unit of cross-sectional area. Oxidation of skeletal muscle ryanodine 1 receptors (RyR1) reduces contractile force as a result of reduced binding of calstabi...

Full description

Saved in:

Bibliographic Details
Main Authors:	Carlos A. Toro, Rita De Gasperi, Abdurrahman Aslan, Nicholas Johnson, Mustafa M. Siddiq, Christine Chow, Wei Zhao, Lauren Harlow, Zachary Graham, Xin-Hua Liu, Junichi Sadoshima, Ravi Iyengar, Christopher P. Cardozo
Format:	Article
Language:	English
Published:	Mary Ann Liebert 2024-11-01
Series:	Neurotrauma Reports
Subjects:	muscle cKO muscle contractility Nox4 SCI mouse models transection SCI
Online Access:	https://www.liebertpub.com/doi/10.1089/neur.2023.0089
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Brd4 expression in CD4 T cells and in microglia promotes neuroinflammation in experimental autoimmune encephalomyelitis
by: Anup Dey, et al.
Published: (2025-06-01)

Analysis of requests for journals <i>Nature Food</i> and <i>npj Science of Food</i> by the data of the SCI-HUB service for the first half of 2020
by: V. Yu. Kornienko
Published: (2020-12-01)

Effect of sodium nitroprusside on parameters of electrical and contractile activities of lower esophageal sphincter unstriped muscles
by: A. O. Stalbovsky, et al.
Published: (2004-06-01)

Inhibition of Contractility of Isolated Caprine Detrusor by the Rho Kinase Inhibitor Fasudil and Reversal by the Guanylyl Cyclase Inhibitor ODQ
by: Niranjana Jeba Jeeviha, MD, et al.
Published: (2025-01-01)

Preface
Published: (2009-01-01)

Time-of-day effects on muscle mitochondria following short-term ablation of satellite cells
by: Ryan E. Kahn, et al.
Published: (2025-07-01)

Development of Home Care Guidelines for the Caregivers of the Patients Being Discharged with Spinal Cord Injury
by: Navdeep Kaur, et al.
Published: (2015-12-01)

Las MiPymes como factor determinante del emprendimiento: un análisis bibliométrico para el periodo 2000- 2020
by: Yolanda Mariana García-Carranza
Published: (2021-10-01)

Obstructive sleep apnoea triggering autonomic dysreflexia: Isn't it time for sleep studies to be routine in SCI?
by: Ameerah Alsaqobi
Published: (2024-01-01)

Photobiomodulation reduces spinal cord edema by decreasing the expression of AQP4 in the astrocytes of male spinal cord injury rats via the JAK2/STAT3 signaling pathway
by: Tingyu Wu, et al.
Published: (2024-12-01)

Antioxidant and antiinflammatory of clove extract (Syzigium aromaticum) in skeletal muscle damage
by: Tyas Sari Ratna Ningrum, et al.
Published: (2025-03-01)

Myofiber structure, sarcoplasmic reticulum Ca2+ handling, and contractile function after muscle‐damaging exercise in humans
by: V. Handegard, et al.
Published: (2025-02-01)

Health status and disability in persons with spinal cord injuries in South Africa and Kenya
by: Conran Joseph, et al.
Published: (2024-09-01)

The storyteller
by: James Danielsen
Published: (2020-03-01)

Curcumin/pEGCG-encapsulated nanoparticles enhance spinal cord injury recovery by regulating CD74 to alleviate oxidative stress and inflammation
by: Tianjun Chen, et al.
Published: (2024-10-01)

Riluzole’s role in treatment of spinal cord injuries – overview of studies on animals and humans
by: Wenancjusz Stołowski, et al.
Published: (2025-05-01)

Outdoor experiences and outdoor-based activities and interventions for individuals with spinal cord injury: a systematic scoping review
by: Anders O. Aaby, et al.
Published: (2025-01-01)

Neuromuscular electrical stimulation training induces myonuclear accretion and hypertrophy in mice without overt signs of muscle damage and regeneration
by: Aurélie Fessard, et al.
Published: (2025-02-01)

The interaction of post-activation potentiation and fatigue on skeletal muscle twitch torque and displacement
by: Georg Langen, et al.
Published: (2025-01-01)

Student’s access to scientific information resources using pirate open access sci-hub
by: Masita Dewi Cahyani, et al.
Published: (2024-10-01)

Design and Local Application of Controlled Released Drug Delivery System of Chitosan Hydrogel Loaded with Selenium Nanoparticle in Spinal Cord Injury-Induced Rat; Evaluation of Antioxidant Changes in Neural Tissue
by: Moosa Javdani, et al.
Published: (2025-04-01)

Bibliometric analysis of public health research in Africa: The overall trend and regional comparisons
by: Kun-Yang Chuang, et al.
Published: (2011-05-01)

Major ozonated autohemotherapy promoted functional recovery following spinal cord injury in adult rats via the inhibition of oxidative stress and inflammation
by: Xia Liwei, et al.
Published: (2024-12-01)

Roles of METTL3 and NLRP3 in pyroptosis and prospects in SCIRI
by: Xiaoqing Guan, et al.
Published: (2025-04-01)

Neuroticism Overestimated? Neuroticism Versus Hypertonia, Pain and Rehabilitation Outcomes in Post-Spinal Cord Injury Patients Rehabilitated Conventionally and with Robotic-Assisted Gait Training
by: Alicja Widuch-Spodyniuk, et al.
Published: (2024-11-01)

Erythrocyte nicotinamide adenine dinucleotide concentration is enhanced by systematic sports participation
by: Barbara Pospieszna, et al.
Published: (2024-10-01)

Nicotinamide adenine dinucleotide supplementation fails to enhance anesthetic recovery in rodents
by: Candida L. Goodnough, et al.
Published: (2025-01-01)

Zearalenone Exposure Damages Skeletal Muscle Through Oxidative Stress and Is Alleviated by Glutathione, Nicotinamide Mononucleotide, and Melatonin
by: Dandan Li, et al.
Published: (2025-04-01)

Coupling of mitochondrial function and skeletal muscle fiber type by a miR‐499/Fnip1/AMPK circuit
by: Jing Liu, et al.
Published: (2016-08-01)

Metagenomic and metabolomic analysis of gut microbiome's role in spinal cord injury recovery in rats
by: Jieqi Zhang, et al.
Published: (2025-03-01)

Reviewing Breakthroughs and Limitations of Implantable and External Medical Device Treatments for Spinal Cord Injury
by: Tooba Wallana, et al.
Published: (2025-07-01)

Scientific estimation on the agriculture subjects using SCI
by: LIU Yan-yang, et al.
Published: (2003-09-01)

Tropical Utopia, Tropical Dystopia: Global South Science Fiction and Critical Approaches to International Politics
by: Fernanda Barasuol, et al.
Published: (2024-12-01)

Life Expectancy After Spinal Cord Injury In a Developing Country-A Retrospective Study At CRP, Bangladesh.
by: Reshma Parvin Nuri, et al.
Published: (2011-10-01)

Virtual Immersive Models for Viewing Social Science Fiction in European Cinema
by: Federico O. Oppedisano, et al.
Published: (2018-06-01)

Autonomic Headache
by: J Gordon Millichap
Published: (2011-09-01)

Promoting mitochondrial fusion is protective against cancer-induced muscle detriments in males and females
by: Francielly Morena, et al.
Published: (2025-08-01)

Impact of Hospitalization on Sarcopenia, NADPH-Oxidase 2, Oxidative Stress, and Low-Grade Endotoxemia in Elderly Patients
by: Chiara Bagnato, et al.
Published: (2025-03-01)

Thick-Filament-Based Regulation and the Determinants of Force Generation
by: Vivek P. Jani, et al.
Published: (2025-03-01)

Les Quotas
by: Marie-Laure Schultze, et al.
Published: (2017-12-01)