EHMT2‐mediated R‐loop formation promotes the malignant progression of prostate cancer via activating Aurora B

EHMT2‐mediated R‐loop formation promotes the malignant progression of prostate cancer via activating Aurora B

Abstract Background Chromosomal instability (CIN), a hallmark of cancer, is commonly linked to poor prognosis in high‐grade prostate cancer (PCa). Paradoxically, excessively high levels of CIN may impair cancer cell viability. Consequently, understanding how tumours adapt to CIN is critical for iden...

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Bibliographic Details
Main Authors: Yuyang Zhang, Mingqin Su, Yiming Chen, Li Cui, Wei Xia, Renfang Xu, Dong Xue, Xiansheng Zhang, Xingliang Feng
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Clinical and Translational Medicine
Subjects:
Aurora B
CIN
CUL3
EHMT2
Online Access:https://doi.org/10.1002/ctm2.70164
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