A segmentation method for lung nodule image sequences based on superpixels and density-based spatial clustering of applications with noise.

The fast and accurate segmentation of lung nodule image sequences is the basis of subsequent processing and diagnostic analyses. However, previous research investigating nodule segmentation algorithms cannot entirely segment cavitary nodules, and the segmentation of juxta-vascular nodules is inaccur...

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Main Authors: Wei Zhang, Xiaolong Zhang, Juanjuan Zhao, Yan Qiang, Qi Tian, Xiaoxian Tang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0184290&type=printable
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author Wei Zhang
Xiaolong Zhang
Juanjuan Zhao
Yan Qiang
Qi Tian
Xiaoxian Tang
author_facet Wei Zhang
Xiaolong Zhang
Juanjuan Zhao
Yan Qiang
Qi Tian
Xiaoxian Tang
author_sort Wei Zhang
collection DOAJ
description The fast and accurate segmentation of lung nodule image sequences is the basis of subsequent processing and diagnostic analyses. However, previous research investigating nodule segmentation algorithms cannot entirely segment cavitary nodules, and the segmentation of juxta-vascular nodules is inaccurate and inefficient. To solve these problems, we propose a new method for the segmentation of lung nodule image sequences based on superpixels and density-based spatial clustering of applications with noise (DBSCAN). First, our method uses three-dimensional computed tomography image features of the average intensity projection combined with multi-scale dot enhancement for preprocessing. Hexagonal clustering and morphological optimized sequential linear iterative clustering (HMSLIC) for sequence image oversegmentation is then proposed to obtain superpixel blocks. The adaptive weight coefficient is then constructed to calculate the distance required between superpixels to achieve precise lung nodules positioning and to obtain the subsequent clustering starting block. Moreover, by fitting the distance and detecting the change in slope, an accurate clustering threshold is obtained. Thereafter, a fast DBSCAN superpixel sequence clustering algorithm, which is optimized by the strategy of only clustering the lung nodules and adaptive threshold, is then used to obtain lung nodule mask sequences. Finally, the lung nodule image sequences are obtained. The experimental results show that our method rapidly, completely and accurately segments various types of lung nodule image sequences.
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spelling doaj-art-9b799aa697744145b281d4f3a0febf6b2025-08-20T02:03:58ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01129e018429010.1371/journal.pone.0184290A segmentation method for lung nodule image sequences based on superpixels and density-based spatial clustering of applications with noise.Wei ZhangXiaolong ZhangJuanjuan ZhaoYan QiangQi TianXiaoxian TangThe fast and accurate segmentation of lung nodule image sequences is the basis of subsequent processing and diagnostic analyses. However, previous research investigating nodule segmentation algorithms cannot entirely segment cavitary nodules, and the segmentation of juxta-vascular nodules is inaccurate and inefficient. To solve these problems, we propose a new method for the segmentation of lung nodule image sequences based on superpixels and density-based spatial clustering of applications with noise (DBSCAN). First, our method uses three-dimensional computed tomography image features of the average intensity projection combined with multi-scale dot enhancement for preprocessing. Hexagonal clustering and morphological optimized sequential linear iterative clustering (HMSLIC) for sequence image oversegmentation is then proposed to obtain superpixel blocks. The adaptive weight coefficient is then constructed to calculate the distance required between superpixels to achieve precise lung nodules positioning and to obtain the subsequent clustering starting block. Moreover, by fitting the distance and detecting the change in slope, an accurate clustering threshold is obtained. Thereafter, a fast DBSCAN superpixel sequence clustering algorithm, which is optimized by the strategy of only clustering the lung nodules and adaptive threshold, is then used to obtain lung nodule mask sequences. Finally, the lung nodule image sequences are obtained. The experimental results show that our method rapidly, completely and accurately segments various types of lung nodule image sequences.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0184290&type=printable
spellingShingle Wei Zhang
Xiaolong Zhang
Juanjuan Zhao
Yan Qiang
Qi Tian
Xiaoxian Tang
A segmentation method for lung nodule image sequences based on superpixels and density-based spatial clustering of applications with noise.
PLoS ONE
title A segmentation method for lung nodule image sequences based on superpixels and density-based spatial clustering of applications with noise.
title_full A segmentation method for lung nodule image sequences based on superpixels and density-based spatial clustering of applications with noise.
title_fullStr A segmentation method for lung nodule image sequences based on superpixels and density-based spatial clustering of applications with noise.
title_full_unstemmed A segmentation method for lung nodule image sequences based on superpixels and density-based spatial clustering of applications with noise.
title_short A segmentation method for lung nodule image sequences based on superpixels and density-based spatial clustering of applications with noise.
title_sort segmentation method for lung nodule image sequences based on superpixels and density based spatial clustering of applications with noise
url https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0184290&type=printable
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