Aging aggravates cognitive dysfunction in spontaneously hypertensive rats by inducing cerebral microvascular endothelial dysfunction.

Aging aggravates cognitive dysfunction in spontaneously hypertensive rats by inducing cerebral microvascular endothelial dysfunction.

Hypertension in the elderly can seriously lead to cerebral microvascular damage and promote the development of vascular cognitive impairment. While endothelial function is crucial in cerebral microvascular protection, it is unclear whether aging exacerbates hypertension-induced cognitive dysfunction...

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Bibliographic Details
Main Authors: Mei Wu, Dandan Li, Feng Qiu, Huifang Nie, Rui Fang, Ziyan Zhong, Hui Yang, Xiaoyuan Lin, Xiangyuan Wang, Hongbo Wen, Lijun Gong, Pan Meng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0316383
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