Harnessing tomato-derived small extracellular vesicles as drug delivery system for cancer therapy

Harnessing tomato-derived small extracellular vesicles as drug delivery system for cancer therapy

Aim This study aims to explore a sustainable and scalable approach using tomato fruit-derived sEVs (TsEVs) to deliver calcitriol for enhanced anticancer effects, addressing challenges of low yield and high costs associated with mammalian cell-derived sEVs.Methods TsEVs were isolated by centrifugatio...

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Bibliographic Details
Main Authors: Kartik Kumar Sarwareddy, Anula Divyash Singh, Sreekanth Patnam, Babiola Annes Sesuraj, spd Ponamgi, Basant Kumar Thakur, Venkata Sasidhar Manda
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Future Science OA
Subjects:
Plant exosomes
vitamin D
calcitriol
drug delivery
cell death
cancer therapy
Online Access:https://www.tandfonline.com/doi/10.1080/20565623.2025.2461956
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