Benefits and harms of perioperative high fraction inspired oxygen for surgical site infection prevention: a protocol for a systematic review and meta-analysis of individual patient data of randomised controlled trials

Benefits and harms of perioperative high fraction inspired oxygen for surgical site infection prevention: a protocol for a systematic review and meta-analysis of individual patient data of randomised controlled trials

Introduction The use of high fraction of inspired oxygen (FiO2) intraoperatively for the prevention of surgical site infection (SSI) remains controversial. Promising results of early randomised controlled trials (RCT) have been replicated with varying success and subsequent meta-analysis are equivoc...

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Main Authors: Paul Myles, Markus W Hollmann, Janet Martin, Andrew Forbes, Benedetta Allegranzi, Kate Leslie, Robert Greif, Matthew TV Chan, Christian S Meyhoff, Marcel GW Dijkgraaf, Stijn W de Jonge, Carlos Ferrando, Kane Pryor, Andrea Kurz, Daniel I Sessler, Pascal Thibon, Marja Boermeester, Rick H Hulskes, Maedeh Zokaei Nikoo, Robert P Weenink, Ozan Akca, F Javier Belda, Gabriel M Gurman, Christina M Scifres, David S McKenna, Jannicke Mellin-Olsen
Format: Article
Language:English
Published: BMJ Publishing Group 2023-10-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/10/e067243.full
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