Allergic rhinitis and the phenomenon of entopy
This article provides a review of the phenomenon of entopy or local atopy from the viewpoint of allergic phenotypes and endotypes. A clinical form of the entopy endotype is local allergic rhinitis, which is still a fertile area for research. The exact mechanisms in the breakdown of allergen toleranc...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2020-10-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/2998 |
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| author | A. V. Klimov O. V. Kalyughin V. V. Klimov V. S. Sviridova |
| author_facet | A. V. Klimov O. V. Kalyughin V. V. Klimov V. S. Sviridova |
| author_sort | A. V. Klimov |
| collection | DOAJ |
| description | This article provides a review of the phenomenon of entopy or local atopy from the viewpoint of allergic phenotypes and endotypes. A clinical form of the entopy endotype is local allergic rhinitis, which is still a fertile area for research. The exact mechanisms in the breakdown of allergen tolerance in entopy remain unclear. The review focuses on the pathogenesis, diagnostic algorithm, and the choice of treatment strategies in local allergic rhinitis. |
| format | Article |
| id | doaj-art-9b6d3b0deed348d98bd2520aef28de53 |
| institution | Kabale University |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2020-10-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-9b6d3b0deed348d98bd2520aef28de532025-08-20T03:37:41ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842020-10-0119313714310.20538/1682-0363-2020-3-137-1431657Allergic rhinitis and the phenomenon of entopyA. V. Klimov0O. V. Kalyughin1V. V. Klimov2V. S. Sviridova3Siberian State Medical UniversitySechenov Moscow State Medical UniversitySiberian State Medical UniversitySiberian State Medical UniversityThis article provides a review of the phenomenon of entopy or local atopy from the viewpoint of allergic phenotypes and endotypes. A clinical form of the entopy endotype is local allergic rhinitis, which is still a fertile area for research. The exact mechanisms in the breakdown of allergen tolerance in entopy remain unclear. The review focuses on the pathogenesis, diagnostic algorithm, and the choice of treatment strategies in local allergic rhinitis.https://bulletin.ssmu.ru/jour/article/view/2998allergensatopyentopyallergen toleranceallergic rhinitislocal allergic rhinitisphenotypesendotypesbiomarkerstype 2 helper t cellst regulatory cells |
| spellingShingle | A. V. Klimov O. V. Kalyughin V. V. Klimov V. S. Sviridova Allergic rhinitis and the phenomenon of entopy Бюллетень сибирской медицины allergens atopy entopy allergen tolerance allergic rhinitis local allergic rhinitis phenotypes endotypes biomarkers type 2 helper t cells t regulatory cells |
| title | Allergic rhinitis and the phenomenon of entopy |
| title_full | Allergic rhinitis and the phenomenon of entopy |
| title_fullStr | Allergic rhinitis and the phenomenon of entopy |
| title_full_unstemmed | Allergic rhinitis and the phenomenon of entopy |
| title_short | Allergic rhinitis and the phenomenon of entopy |
| title_sort | allergic rhinitis and the phenomenon of entopy |
| topic | allergens atopy entopy allergen tolerance allergic rhinitis local allergic rhinitis phenotypes endotypes biomarkers type 2 helper t cells t regulatory cells |
| url | https://bulletin.ssmu.ru/jour/article/view/2998 |
| work_keys_str_mv | AT avklimov allergicrhinitisandthephenomenonofentopy AT ovkalyughin allergicrhinitisandthephenomenonofentopy AT vvklimov allergicrhinitisandthephenomenonofentopy AT vssviridova allergicrhinitisandthephenomenonofentopy |