TIM3 and TIGIT-expressing CD4 T cells are impacted by kidney transplantation and associated with risk of infection

TIM3 and TIGIT-expressing CD4 T cells are impacted by kidney transplantation and associated with risk of infection

IntroductionOlder kidney transplant patients experience higher rates of infection compared with younger transplant patients suggesting the impact of age-associated immune dysfunction. However, little is known about the impact of immunosuppression including antithymocyte globulin (ATG) induction, as...

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Bibliographic Details
Main Authors: Harry Pickering, Subha Sen, Monica Cappelletti, Erik L. Lum, Suphamai Bunnapradist, Elaine F. Reed, Joanna M. Schaenman
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
T cell
immunosuppression
antithymocyte globulin
kidney transplantation
infection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1550154/full
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