Impact of race and ethnicity on clinical outcomes and recurrence post‐ureteral reconstruction

Abstract Introduction Ureteral stricture disease (UTSD) poses significant challenges in reconstructive urology, with recent advances highlighting disparities in healthcare outcomes based on race and ethnicity. This study investigates the impact of race and ethnicity on clinical outcomes following ur...

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Main Authors: Dhruv Puri, Eric Cho, Kian Ahmadieh, Nishant Garg, Cesar Delgado, Benjamin Cedars, Michael Witthaus, Michael Pan, Jill C. Buckley
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:BJUI Compass
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Online Access:https://doi.org/10.1002/bco2.450
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author Dhruv Puri
Eric Cho
Kian Ahmadieh
Nishant Garg
Cesar Delgado
Benjamin Cedars
Michael Witthaus
Michael Pan
Jill C. Buckley
author_facet Dhruv Puri
Eric Cho
Kian Ahmadieh
Nishant Garg
Cesar Delgado
Benjamin Cedars
Michael Witthaus
Michael Pan
Jill C. Buckley
author_sort Dhruv Puri
collection DOAJ
description Abstract Introduction Ureteral stricture disease (UTSD) poses significant challenges in reconstructive urology, with recent advances highlighting disparities in healthcare outcomes based on race and ethnicity. This study investigates the impact of race and ethnicity on clinical outcomes following ureteral reconstruction. Methods We conducted a single‐centre prospective analysis of 233 patients who underwent ureteral reconstruction for UTSD from 2014 to 2023. Patient demographics, clinical characteristics, surgical details and outcomes were collected. Patients were stratified by race (White vs. non‐White) and ethnicity (Hispanic vs. non‐Hispanic). Statistical analyses included Kruskal–Wallis, Mann–Whitney U tests, ANOVA, Kaplan–Meier analysis and multivariate logistic regression. Results Our cohort included 233 patients who underwent ureteroplasty with 108 (46.4%) non‐White patients, and 71 (30.5%) were Hispanic. No significant differences were found in recurrence rates, complications, or stricture‐free survival between racial and ethnic groups. Prior reconstructions were more prevalent among non‐White patients (26.9% vs. 16.0%; p = 0.043). Unadjusted and adjusted regressions showed significant associations between non‐White race (unadjusted β = 0.76, p = 0.008; adjusted β = 0.82, p = 0.008) and Hispanic ethnicity (unadjusted β = 0.70, p = 0.025; adjusted β = 0.79, p = 0.020) with increased stricture lengths. Conclusion This study highlights that although recurrence and complication rates do not significantly differ by race or ethnicity, disparities exist in clinical presentations, with non‐White and Hispanic patients presenting with longer stricture lengths and higher body mass index. These findings underscore the need for targeted interventions to address underlying disparities in healthcare delivery and access.
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spelling doaj-art-9b64385121eb425884db8b7260bd7fdc2025-08-20T02:52:46ZengWileyBJUI Compass2688-45262024-12-015121255126210.1002/bco2.450Impact of race and ethnicity on clinical outcomes and recurrence post‐ureteral reconstructionDhruv Puri0Eric Cho1Kian Ahmadieh2Nishant Garg3Cesar Delgado4Benjamin Cedars5Michael Witthaus6Michael Pan7Jill C. Buckley8Department of Urology UC San Diego School of Medicine La Jolla California USAKaiser Permanente, Redwood City Medical Center San Francisco California USADepartment of Urology UC San Diego School of Medicine La Jolla California USADepartment of Urology UC San Diego School of Medicine La Jolla California USADepartment of Urology UC San Diego School of Medicine La Jolla California USADepartment of Urology UC San Diego School of Medicine La Jolla California USAUniversity of Maryland Capital Region Medical Center Baltimore Maryland USAKelsey‐Seybold Clinic Houston Texas USADepartment of Urology UC San Diego School of Medicine La Jolla California USAAbstract Introduction Ureteral stricture disease (UTSD) poses significant challenges in reconstructive urology, with recent advances highlighting disparities in healthcare outcomes based on race and ethnicity. This study investigates the impact of race and ethnicity on clinical outcomes following ureteral reconstruction. Methods We conducted a single‐centre prospective analysis of 233 patients who underwent ureteral reconstruction for UTSD from 2014 to 2023. Patient demographics, clinical characteristics, surgical details and outcomes were collected. Patients were stratified by race (White vs. non‐White) and ethnicity (Hispanic vs. non‐Hispanic). Statistical analyses included Kruskal–Wallis, Mann–Whitney U tests, ANOVA, Kaplan–Meier analysis and multivariate logistic regression. Results Our cohort included 233 patients who underwent ureteroplasty with 108 (46.4%) non‐White patients, and 71 (30.5%) were Hispanic. No significant differences were found in recurrence rates, complications, or stricture‐free survival between racial and ethnic groups. Prior reconstructions were more prevalent among non‐White patients (26.9% vs. 16.0%; p = 0.043). Unadjusted and adjusted regressions showed significant associations between non‐White race (unadjusted β = 0.76, p = 0.008; adjusted β = 0.82, p = 0.008) and Hispanic ethnicity (unadjusted β = 0.70, p = 0.025; adjusted β = 0.79, p = 0.020) with increased stricture lengths. Conclusion This study highlights that although recurrence and complication rates do not significantly differ by race or ethnicity, disparities exist in clinical presentations, with non‐White and Hispanic patients presenting with longer stricture lengths and higher body mass index. These findings underscore the need for targeted interventions to address underlying disparities in healthcare delivery and access.https://doi.org/10.1002/bco2.450health disparitiesrace and ethnicityrobot‐assisted ureteroplastyureteral stricture disease
spellingShingle Dhruv Puri
Eric Cho
Kian Ahmadieh
Nishant Garg
Cesar Delgado
Benjamin Cedars
Michael Witthaus
Michael Pan
Jill C. Buckley
Impact of race and ethnicity on clinical outcomes and recurrence post‐ureteral reconstruction
BJUI Compass
health disparities
race and ethnicity
robot‐assisted ureteroplasty
ureteral stricture disease
title Impact of race and ethnicity on clinical outcomes and recurrence post‐ureteral reconstruction
title_full Impact of race and ethnicity on clinical outcomes and recurrence post‐ureteral reconstruction
title_fullStr Impact of race and ethnicity on clinical outcomes and recurrence post‐ureteral reconstruction
title_full_unstemmed Impact of race and ethnicity on clinical outcomes and recurrence post‐ureteral reconstruction
title_short Impact of race and ethnicity on clinical outcomes and recurrence post‐ureteral reconstruction
title_sort impact of race and ethnicity on clinical outcomes and recurrence post ureteral reconstruction
topic health disparities
race and ethnicity
robot‐assisted ureteroplasty
ureteral stricture disease
url https://doi.org/10.1002/bco2.450
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