A retrospective single center analysis of fetuses with region of homozygosity detected by single nucleotide polymorphism array
Abstract We assessed the incidence and clinical significance of the fetal region of homozygosity (ROH) detected using single nucleotide polymorphism (SNP) array by analyzing clinical information and pregnancy outcomes. We collected data on 6176 mid- and late pregnancies. All fetuses were subjected t...
Saved in:
| Main Authors: | Xiufen Bu, Xiuyun Yu, Li Zeng, Guo Zeng, Rong Tan, Can Peng, Shihao Zhou, Siyuan Linpeng, Jing Liu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-98497-9 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Pitfalls in the diagnosis of apparent homozygous mutations: two cases of IL10RA deficiency inflammatory bowel disease and a literature review
by: Xiu Shi, et al.
Published: (2025-07-01) -
Whole genome uniparental isodisomy detected using single nucleotide polymorphism (SNP) microarray in molar pregnancy: a case report
by: Onyinye O. Okonkwo, et al.
Published: (2025-02-01) -
Analysis of runs of homozygosity in Yeonsan Ogye chickens using 600K single nucleotide polymorphism arrays
by: Jaewon Kim, et al.
Published: (2025-05-01) -
ImprintCap, a powerful NGS-based technology to investigate the molecular background of imprinting disorders
by: Frédéric Brioude, et al.
Published: (2025-07-01) -
HB H DISEASE CAUSED BY UNIPARENTAL DISOMY: FIRST REPORT OF THE αT-SAUDIΑ MUTATION IN THE CHINESE POPULATION
by: Ge Wang, et al.
Published: (2024-08-01)