Predictive Risk Factors of Intestinal Necrosis in Patients with Mesenteric Venous Thrombosis: Retrospective Study from a Single Center
Purposes. Mesenteric venous thrombosis (MVT) is a serious condition. The current study aimed to identify risk factors of intestinal necrosis (IN) in patients with MVT to predict the onset of patients. Methods. Data pertaining to patients diagnosed with MVT between 2014 and May 2018 were reviewed. Pa...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Canadian Journal of Gastroenterology and Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2019/8906803 |
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| author | Yong Wang Rui Zhao Lin Xia Ya-Ping Cui Yong Zhou Xiao-Ting Wu |
| author_facet | Yong Wang Rui Zhao Lin Xia Ya-Ping Cui Yong Zhou Xiao-Ting Wu |
| author_sort | Yong Wang |
| collection | DOAJ |
| description | Purposes. Mesenteric venous thrombosis (MVT) is a serious condition. The current study aimed to identify risk factors of intestinal necrosis (IN) in patients with MVT to predict the onset of patients. Methods. Data pertaining to patients diagnosed with MVT between 2014 and May 2018 were reviewed. Patients’ characteristics and risk factors of IN were assessed. Results. Seventy-eight patients were included in our study, of whom all cases were diagnosed as superior mesenteric venous thrombosis. There were fifty-eight cases (74%) with intestinal necrosis and twenty cases (26%) without intestinal necrosis. Multivariate analysis of factors associated with IN was organ failure (odds ratio (OR): 4.1; 95% confidence interval (95%CI): 1.26–8.59; P=0.028), elevated serum lactate (OR:3.6; 95% CI: 1.51–5.47; P=0.024), bowel loop dilation on computerized tomography (CT) scan (OR: 2.8; 95% CI: 1.32–7.23; P=0.031), and the time between onset of symptoms and operation (OR: 4.8; 95% CI: 1.36–9.89; P=0.012). Area under the receiver operating characteristics curve for the diagnosis of IN with MVT was 0.901 (95%CI: 0.809–0.993; P=0.000) depending on the different number of predictive factors. Conclusion. Predictive risk factors for IN with MVT were organ failure, elevated serum lactate level, bowel loop dilation on CT, and the time between onset of symptoms and operation. However, this result is from a retrospective study and further long-term, large-sample prospective studies are required to confirm this finding. |
| format | Article |
| id | doaj-art-9b5d03e36121446e8fb64040d5d8ff8f |
| institution | OA Journals |
| issn | 2291-2789 2291-2797 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology and Hepatology |
| spelling | doaj-art-9b5d03e36121446e8fb64040d5d8ff8f2025-08-20T02:20:26ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972019-01-01201910.1155/2019/89068038906803Predictive Risk Factors of Intestinal Necrosis in Patients with Mesenteric Venous Thrombosis: Retrospective Study from a Single CenterYong Wang0Rui Zhao1Lin Xia2Ya-Ping Cui3Yong Zhou4Xiao-Ting Wu5Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, ChinaPurposes. Mesenteric venous thrombosis (MVT) is a serious condition. The current study aimed to identify risk factors of intestinal necrosis (IN) in patients with MVT to predict the onset of patients. Methods. Data pertaining to patients diagnosed with MVT between 2014 and May 2018 were reviewed. Patients’ characteristics and risk factors of IN were assessed. Results. Seventy-eight patients were included in our study, of whom all cases were diagnosed as superior mesenteric venous thrombosis. There were fifty-eight cases (74%) with intestinal necrosis and twenty cases (26%) without intestinal necrosis. Multivariate analysis of factors associated with IN was organ failure (odds ratio (OR): 4.1; 95% confidence interval (95%CI): 1.26–8.59; P=0.028), elevated serum lactate (OR:3.6; 95% CI: 1.51–5.47; P=0.024), bowel loop dilation on computerized tomography (CT) scan (OR: 2.8; 95% CI: 1.32–7.23; P=0.031), and the time between onset of symptoms and operation (OR: 4.8; 95% CI: 1.36–9.89; P=0.012). Area under the receiver operating characteristics curve for the diagnosis of IN with MVT was 0.901 (95%CI: 0.809–0.993; P=0.000) depending on the different number of predictive factors. Conclusion. Predictive risk factors for IN with MVT were organ failure, elevated serum lactate level, bowel loop dilation on CT, and the time between onset of symptoms and operation. However, this result is from a retrospective study and further long-term, large-sample prospective studies are required to confirm this finding.http://dx.doi.org/10.1155/2019/8906803 |
| spellingShingle | Yong Wang Rui Zhao Lin Xia Ya-Ping Cui Yong Zhou Xiao-Ting Wu Predictive Risk Factors of Intestinal Necrosis in Patients with Mesenteric Venous Thrombosis: Retrospective Study from a Single Center Canadian Journal of Gastroenterology and Hepatology |
| title | Predictive Risk Factors of Intestinal Necrosis in Patients with Mesenteric Venous Thrombosis: Retrospective Study from a Single Center |
| title_full | Predictive Risk Factors of Intestinal Necrosis in Patients with Mesenteric Venous Thrombosis: Retrospective Study from a Single Center |
| title_fullStr | Predictive Risk Factors of Intestinal Necrosis in Patients with Mesenteric Venous Thrombosis: Retrospective Study from a Single Center |
| title_full_unstemmed | Predictive Risk Factors of Intestinal Necrosis in Patients with Mesenteric Venous Thrombosis: Retrospective Study from a Single Center |
| title_short | Predictive Risk Factors of Intestinal Necrosis in Patients with Mesenteric Venous Thrombosis: Retrospective Study from a Single Center |
| title_sort | predictive risk factors of intestinal necrosis in patients with mesenteric venous thrombosis retrospective study from a single center |
| url | http://dx.doi.org/10.1155/2019/8906803 |
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