Metastatic Periampullary Tumor from Hepatocellular Carcinoma Presenting as Gastrointestinal Bleeding
Periampullary tumors constitute a number of diverse neoplastic lesions located within 2 cm of the major duodenal papilla; among these, metastatic lesions account for only a small proportion of the periampullary tumors. To our knowledge, a metastatic periampullary tumor from hepatocellular carcinoma...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/732140 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832561994708811776 |
|---|---|
| author | Amir Kashani Nicholas N. Nissen Maha Guindi Laith H. Jamil |
| author_facet | Amir Kashani Nicholas N. Nissen Maha Guindi Laith H. Jamil |
| author_sort | Amir Kashani |
| collection | DOAJ |
| description | Periampullary tumors constitute a number of diverse neoplastic lesions located within 2 cm of the major duodenal papilla; among these, metastatic lesions account for only a small proportion of the periampullary tumors. To our knowledge, a metastatic periampullary tumor from hepatocellular carcinoma has never been reported. A 62-year-old male reported to our institute for fatigue and low hemoglobin. His medical history was remarkable for multifocal hepatocellular carcinoma (HCC) treated with selective transcatheter arterial chemoembolization (TACE). An esophagogastroduodenoscopy (EGD) was performed which revealed a periampullary mass. Histopathology was consistent with metastatic moderately differentiated HCC. Two endoloops were deployed around the base of the mass one month apart. The mass eventually sloughed off and patient’s hemoglobin level stabilized. We postulated that periampullary metastasis in this patient was the result of tumor fragments migration through the biliary tracts and that TACE which increases tumor fragments burden might have played a contributory role. Metastasis of HCC to the gastrointestinal (GI) tract should be considered as a cause of GI bleeding. |
| format | Article |
| id | doaj-art-9b5c0b8b026f4facbe1431a7ec60444a |
| institution | Kabale University |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-9b5c0b8b026f4facbe1431a7ec60444a2025-02-03T01:23:44ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362015-01-01201510.1155/2015/732140732140Metastatic Periampullary Tumor from Hepatocellular Carcinoma Presenting as Gastrointestinal BleedingAmir Kashani0Nicholas N. Nissen1Maha Guindi2Laith H. Jamil3Department of Gastroenterology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USAHepatobiliary and Pancreatic Surgery, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USADepartment of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USADepartment of Gastroenterology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USAPeriampullary tumors constitute a number of diverse neoplastic lesions located within 2 cm of the major duodenal papilla; among these, metastatic lesions account for only a small proportion of the periampullary tumors. To our knowledge, a metastatic periampullary tumor from hepatocellular carcinoma has never been reported. A 62-year-old male reported to our institute for fatigue and low hemoglobin. His medical history was remarkable for multifocal hepatocellular carcinoma (HCC) treated with selective transcatheter arterial chemoembolization (TACE). An esophagogastroduodenoscopy (EGD) was performed which revealed a periampullary mass. Histopathology was consistent with metastatic moderately differentiated HCC. Two endoloops were deployed around the base of the mass one month apart. The mass eventually sloughed off and patient’s hemoglobin level stabilized. We postulated that periampullary metastasis in this patient was the result of tumor fragments migration through the biliary tracts and that TACE which increases tumor fragments burden might have played a contributory role. Metastasis of HCC to the gastrointestinal (GI) tract should be considered as a cause of GI bleeding.http://dx.doi.org/10.1155/2015/732140 |
| spellingShingle | Amir Kashani Nicholas N. Nissen Maha Guindi Laith H. Jamil Metastatic Periampullary Tumor from Hepatocellular Carcinoma Presenting as Gastrointestinal Bleeding Case Reports in Gastrointestinal Medicine |
| title | Metastatic Periampullary Tumor from Hepatocellular Carcinoma Presenting as Gastrointestinal Bleeding |
| title_full | Metastatic Periampullary Tumor from Hepatocellular Carcinoma Presenting as Gastrointestinal Bleeding |
| title_fullStr | Metastatic Periampullary Tumor from Hepatocellular Carcinoma Presenting as Gastrointestinal Bleeding |
| title_full_unstemmed | Metastatic Periampullary Tumor from Hepatocellular Carcinoma Presenting as Gastrointestinal Bleeding |
| title_short | Metastatic Periampullary Tumor from Hepatocellular Carcinoma Presenting as Gastrointestinal Bleeding |
| title_sort | metastatic periampullary tumor from hepatocellular carcinoma presenting as gastrointestinal bleeding |
| url | http://dx.doi.org/10.1155/2015/732140 |
| work_keys_str_mv | AT amirkashani metastaticperiampullarytumorfromhepatocellularcarcinomapresentingasgastrointestinalbleeding AT nicholasnnissen metastaticperiampullarytumorfromhepatocellularcarcinomapresentingasgastrointestinalbleeding AT mahaguindi metastaticperiampullarytumorfromhepatocellularcarcinomapresentingasgastrointestinalbleeding AT laithhjamil metastaticperiampullarytumorfromhepatocellularcarcinomapresentingasgastrointestinalbleeding |