Cardiovascular and nephrological risk in patients with chronic kidney disease in ambulatory care.

Patients with chronic kidney disease (CKD) have higher than in general population all-cause and cardiovascular mortality. Arterial hypertension (HTN) is a powerful potentially modifiable risk factor that affects the majority of patients with chronic kidney disease and one of the main causes of end s...

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Main Authors: O. Kuryata, V. Semenov
Format: Article
Language:English
Published: Dnipro State Medical University 2019-11-01
Series:Medičnì Perspektivi
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Online Access:http://journals.uran.ua/index.php/2307-0404/article/view/181874
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author O. Kuryata
V. Semenov
author_facet O. Kuryata
V. Semenov
author_sort O. Kuryata
collection DOAJ
description Patients with chronic kidney disease (CKD) have higher than in general population all-cause and cardiovascular mortality. Arterial hypertension (HTN) is a powerful potentially modifiable risk factor that affects the majority of patients with chronic kidney disease and one of the main causes of end stage renal disease worldwide. Existing tools for assessment of risk of CKD progression do not take into account arterial hypertension. The aim – to investigate the association between cardiovascular and nephrological risk factors in patients with CKD in ambulatory practice. The study was carried out in the Center of Nephrology Care in Mechnikov Dnipropetrovsk Regional Hospital, Dnipro, Ukraine. 278 patients (114 males and 164 women, aged 41 [31;61] years) with CKD (stages 1-3) who were followed-up in ambulatory care, but required diagnosis or treatment revision were enrolled to the study. All patients were examined and followed-up according to local and European standards. Females slightly prevailed in our study, gender distribution varied insufficiently in groups by CKD progression risk. Elevation of risk of CKD progression was accompanied by rise of prevalence of diabetes mellitus, left ventricle hypertrophy, proteinuria and HTN.  Risk of CKD progression correlated with age, systolic and diastolic blood pressure, erythrocyte sedimentation rate, total cholesterol, glomerular filtration rate, albumin excretion rate, duration of HTN and body mass index. Rise of cardiovascular risk was accompanied by rise of proportion of patients with high risk of CKD progression. Increase in risk of CKD progression is associated with rise of burden of cardiovascular risk factors. HTN and blood pressure values should be accounted for assessment of risk of CKD progression.
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spelling doaj-art-9b5b70de457d4f719fd4e2f165230c8d2025-08-20T02:51:59ZengDnipro State Medical UniversityMedičnì Perspektivi2307-04042019-11-01243152110.26641/2307-0404.2019.3.181874181874Cardiovascular and nephrological risk in patients with chronic kidney disease in ambulatory care.O. KuryataV. SemenovPatients with chronic kidney disease (CKD) have higher than in general population all-cause and cardiovascular mortality. Arterial hypertension (HTN) is a powerful potentially modifiable risk factor that affects the majority of patients with chronic kidney disease and one of the main causes of end stage renal disease worldwide. Existing tools for assessment of risk of CKD progression do not take into account arterial hypertension. The aim – to investigate the association between cardiovascular and nephrological risk factors in patients with CKD in ambulatory practice. The study was carried out in the Center of Nephrology Care in Mechnikov Dnipropetrovsk Regional Hospital, Dnipro, Ukraine. 278 patients (114 males and 164 women, aged 41 [31;61] years) with CKD (stages 1-3) who were followed-up in ambulatory care, but required diagnosis or treatment revision were enrolled to the study. All patients were examined and followed-up according to local and European standards. Females slightly prevailed in our study, gender distribution varied insufficiently in groups by CKD progression risk. Elevation of risk of CKD progression was accompanied by rise of prevalence of diabetes mellitus, left ventricle hypertrophy, proteinuria and HTN.  Risk of CKD progression correlated with age, systolic and diastolic blood pressure, erythrocyte sedimentation rate, total cholesterol, glomerular filtration rate, albumin excretion rate, duration of HTN and body mass index. Rise of cardiovascular risk was accompanied by rise of proportion of patients with high risk of CKD progression. Increase in risk of CKD progression is associated with rise of burden of cardiovascular risk factors. HTN and blood pressure values should be accounted for assessment of risk of CKD progression.http://journals.uran.ua/index.php/2307-0404/article/view/181874cardiovascular riskchronic kidney diseaseprogressionarterial hypertension
spellingShingle O. Kuryata
V. Semenov
Cardiovascular and nephrological risk in patients with chronic kidney disease in ambulatory care.
Medičnì Perspektivi
cardiovascular risk
chronic kidney disease
progression
arterial hypertension
title Cardiovascular and nephrological risk in patients with chronic kidney disease in ambulatory care.
title_full Cardiovascular and nephrological risk in patients with chronic kidney disease in ambulatory care.
title_fullStr Cardiovascular and nephrological risk in patients with chronic kidney disease in ambulatory care.
title_full_unstemmed Cardiovascular and nephrological risk in patients with chronic kidney disease in ambulatory care.
title_short Cardiovascular and nephrological risk in patients with chronic kidney disease in ambulatory care.
title_sort cardiovascular and nephrological risk in patients with chronic kidney disease in ambulatory care
topic cardiovascular risk
chronic kidney disease
progression
arterial hypertension
url http://journals.uran.ua/index.php/2307-0404/article/view/181874
work_keys_str_mv AT okuryata cardiovascularandnephrologicalriskinpatientswithchronickidneydiseaseinambulatorycare
AT vsemenov cardiovascularandnephrologicalriskinpatientswithchronickidneydiseaseinambulatorycare