Sex-specific changes in energy demand during the preplaque stage in a transgenic Alzheimer’s mouse model

Abstract Background Cognitive deficits and brain glucose hypometabolism, lipid peroxidation and mitochondrial dysfunction are early pathological events in murine models and patients with Alzheimer’s disease (AD). Data from our previous research indicate that transgenic mice of the APP23 line, a muri...

Full description

Saved in:
Bibliographic Details
Main Authors: Rongwan Sun, Leonie-Kim Zimbalski, Stefanie Schreyer, David Baidoe-Ansah, Aida Harutyunyan, Arnd Heuser, Rachel N. Lippert, Joachim Spranger, Knut Mai, Sebastian Brachs
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Biology of Sex Differences
Online Access:https://doi.org/10.1186/s13293-025-00737-0
Tags: Add Tag
No Tags, Be the first to tag this record!