Infection length and host environment influence on Plasmodium falciparum dry season reservoir

Infection length and host environment influence on Plasmodium falciparum dry season reservoir

Abstract Persistence of malaria parasites in asymptomatic hosts is crucial in areas of seasonally-interrupted transmission, where P. falciparum bridges wet seasons months apart. During the dry season, infected erythrocytes exhibit extended circulation with reduced cytoadherence, increasing the risk...

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Main Authors: Carolina M Andrade, Manuela Carrasquilla, Usama Dabbas, Jessica Briggs, Hannah van Dijk, Nikolay Sergeev, Awa Sissoko, Moussa Niangaly, Christina Ntalla, Emily LaVerriere, Jeff Skinner, Klara Golob, Jeremy Richter, Hamidou Cisse, Shanping Li, Jason A Hendry, Muhammad Asghar, Didier Doumtabe, Anna Farnert, Thomas Ruppert, Daniel E Neafsey, Kassoum Kayentao, Safiatou Doumbo, Aissata Ongoiba, Peter D Crompton, Boubacar Traore, Bryan Greenhouse, Silvia Portugal
Format: Article
Language:English
Published: Springer Nature 2024-09-01
Series:EMBO Molecular Medicine
Subjects:
Malaria
Dry Season
Sensing
Infection Length
Asymptomatic
Online Access:https://doi.org/10.1038/s44321-024-00127-w
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