A spontaneous reduction in tumor size of a thymic carcinoma: a case report

Abstract Background Spontaneous regression of thymic carcinoma is extremely rare. We report a case of a resected thymic carcinoma with preoperative spontaneous regression in a 67-year-old woman. Case presentation The patient presented with low-grade fever and anterior chest pain. Chest computed tomo...

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Main Authors: Shoei Kuroki, Takanori Ayabe, Hiroyuki Tanaka, Hiroshi Nakada, Ryo Maeda
Format: Article
Language:English
Published: Japan Surgical Society 2022-08-01
Series:Surgical Case Reports
Subjects:
Online Access:https://doi.org/10.1186/s40792-022-01510-w
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author Shoei Kuroki
Takanori Ayabe
Hiroyuki Tanaka
Hiroshi Nakada
Ryo Maeda
author_facet Shoei Kuroki
Takanori Ayabe
Hiroyuki Tanaka
Hiroshi Nakada
Ryo Maeda
author_sort Shoei Kuroki
collection DOAJ
description Abstract Background Spontaneous regression of thymic carcinoma is extremely rare. We report a case of a resected thymic carcinoma with preoperative spontaneous regression in a 67-year-old woman. Case presentation The patient presented with low-grade fever and anterior chest pain. Chest computed tomography (CT) showed a 55 × 43 mm exophytic heterogeneously enhancing mass showing some areas of necrosis. Chest CT done one day preoperatively revealed that the tumor had rapidly shrunk for one month. Surgical resection was performed to obtain a definitive diagnosis and achieve complete resection, yielding a postoperative diagnosis of thymic carcinoma. The patient survived without signs of recurrence for 12 months postoperatively. Conclusions Mediastinal tumors with necrosis demonstrating spontaneous regression should include thymic carcinomas in the differential diagnosis.
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publishDate 2022-08-01
publisher Japan Surgical Society
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series Surgical Case Reports
spelling doaj-art-9b3a2dd2fa6f4e9e9657fc01690b6ca22025-08-20T03:57:08ZengJapan Surgical SocietySurgical Case Reports2198-77932022-08-01811310.1186/s40792-022-01510-wA spontaneous reduction in tumor size of a thymic carcinoma: a case reportShoei Kuroki0Takanori Ayabe1Hiroyuki Tanaka2Hiroshi Nakada3Ryo Maeda4Department of Thoracic and Breast Surgery, Faculty of Medicine, University of MiyazakiDepartment of Thoracic and Breast Surgery, Faculty of Medicine, University of MiyazakiDepartment of Pathology, University of MiyazakiDepartment of Radiology, University of MiyazakiDepartment of Thoracic and Breast Surgery, Faculty of Medicine, University of MiyazakiAbstract Background Spontaneous regression of thymic carcinoma is extremely rare. We report a case of a resected thymic carcinoma with preoperative spontaneous regression in a 67-year-old woman. Case presentation The patient presented with low-grade fever and anterior chest pain. Chest computed tomography (CT) showed a 55 × 43 mm exophytic heterogeneously enhancing mass showing some areas of necrosis. Chest CT done one day preoperatively revealed that the tumor had rapidly shrunk for one month. Surgical resection was performed to obtain a definitive diagnosis and achieve complete resection, yielding a postoperative diagnosis of thymic carcinoma. The patient survived without signs of recurrence for 12 months postoperatively. Conclusions Mediastinal tumors with necrosis demonstrating spontaneous regression should include thymic carcinomas in the differential diagnosis.https://doi.org/10.1186/s40792-022-01510-wSpontaneous regressionSurgeryThymic carcinoma
spellingShingle Shoei Kuroki
Takanori Ayabe
Hiroyuki Tanaka
Hiroshi Nakada
Ryo Maeda
A spontaneous reduction in tumor size of a thymic carcinoma: a case report
Surgical Case Reports
Spontaneous regression
Surgery
Thymic carcinoma
title A spontaneous reduction in tumor size of a thymic carcinoma: a case report
title_full A spontaneous reduction in tumor size of a thymic carcinoma: a case report
title_fullStr A spontaneous reduction in tumor size of a thymic carcinoma: a case report
title_full_unstemmed A spontaneous reduction in tumor size of a thymic carcinoma: a case report
title_short A spontaneous reduction in tumor size of a thymic carcinoma: a case report
title_sort spontaneous reduction in tumor size of a thymic carcinoma a case report
topic Spontaneous regression
Surgery
Thymic carcinoma
url https://doi.org/10.1186/s40792-022-01510-w
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