Structural basis for transcription activation through cooperative recruitment of MntR

Abstract Bacillus subtilis MntR is a dual regulatory protein that responds to heightened Mn2+ availability in the cell by both repressing the expression of uptake transporters and activating the expression of efflux proteins. Recent work indicates that, in its role as an activator, MntR binds severa...

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Bibliographic Details
Main Authors: Haoyuan Shi, Yu Fu, Vilmante Kodyte, Amelie Andreas, Ankita J. Sachla, Keikilani Miller, Ritu Shrestha, John D. Helmann, Arthur Glasfeld, Shivani Ahuja
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57412-6
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