Acute Hepatic Porphyria – Minireview
Acute Hepatic Porphyria (AHP) is an uncommon and hereditary illness that belongs to a group of disorders known as porphyries. This condition results from a deficiency of the porphobilinogen deaminase enzyme, which plays a role in heme production, a crucial component of haemoglobin in the bloodstream...
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| Format: | Article |
| Language: | English |
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Bucharest College of Physicians
2023-03-01
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| Series: | Modern Medicine |
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| Online Access: | https://medicinamoderna.ro/wp-content/uploads/2023/03/Acute-Hepatic-Porphyria-%E2%80%93-Minireview.pdf |
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| author | Aida SAVU Andrei EDU Lucian NEGREANU |
| author_facet | Aida SAVU Andrei EDU Lucian NEGREANU |
| author_sort | Aida SAVU |
| collection | DOAJ |
| description | Acute Hepatic Porphyria (AHP) is an uncommon and hereditary illness that belongs to a group of disorders known as porphyries. This condition results from a deficiency of the porphobilinogen deaminase enzyme, which plays a role in heme production, a crucial component of haemoglobin in the bloodstream. This deficiency leads to the accumulation of substances called porphyrins in the body, which can trigger the appearance of severe and potentially life-threatening symptoms. In the following, we will discuss classifications - with a focus on the similarities and differences between subtypes of porphyria, the pathophysiology of acute hepatic porphyria, risk factors – and their influence on the onset of the disease, clinical manifestations, diagnosis, and management – both curative and symptomatic, all of which play a very important role in understanding this rare condition. |
| format | Article |
| id | doaj-art-9b248da9900d4de7af0469c7a5e9666e |
| institution | OA Journals |
| issn | 1223-0472 2360-2473 |
| language | English |
| publishDate | 2023-03-01 |
| publisher | Bucharest College of Physicians |
| record_format | Article |
| series | Modern Medicine |
| spelling | doaj-art-9b248da9900d4de7af0469c7a5e9666e2025-08-20T02:20:26ZengBucharest College of PhysiciansModern Medicine1223-04722360-24732023-03-013011316https://doi.org/10.31689/rmm.2023.30.1.13Acute Hepatic Porphyria – MinireviewAida SAVU0Andrei EDU1Lucian NEGREANU2https://orcid.org/0000-0003-3042-0754”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania”Carol Davila” University of Medicine and Pharmacy, Bucharest, RomaniaAcute Hepatic Porphyria (AHP) is an uncommon and hereditary illness that belongs to a group of disorders known as porphyries. This condition results from a deficiency of the porphobilinogen deaminase enzyme, which plays a role in heme production, a crucial component of haemoglobin in the bloodstream. This deficiency leads to the accumulation of substances called porphyrins in the body, which can trigger the appearance of severe and potentially life-threatening symptoms. In the following, we will discuss classifications - with a focus on the similarities and differences between subtypes of porphyria, the pathophysiology of acute hepatic porphyria, risk factors – and their influence on the onset of the disease, clinical manifestations, diagnosis, and management – both curative and symptomatic, all of which play a very important role in understanding this rare condition.https://medicinamoderna.ro/wp-content/uploads/2023/03/Acute-Hepatic-Porphyria-%E2%80%93-Minireview.pdfporphyriahaemoglobinacute hepatic porphyria (ahp) |
| spellingShingle | Aida SAVU Andrei EDU Lucian NEGREANU Acute Hepatic Porphyria – Minireview Modern Medicine porphyria haemoglobin acute hepatic porphyria (ahp) |
| title | Acute Hepatic Porphyria – Minireview |
| title_full | Acute Hepatic Porphyria – Minireview |
| title_fullStr | Acute Hepatic Porphyria – Minireview |
| title_full_unstemmed | Acute Hepatic Porphyria – Minireview |
| title_short | Acute Hepatic Porphyria – Minireview |
| title_sort | acute hepatic porphyria minireview |
| topic | porphyria haemoglobin acute hepatic porphyria (ahp) |
| url | https://medicinamoderna.ro/wp-content/uploads/2023/03/Acute-Hepatic-Porphyria-%E2%80%93-Minireview.pdf |
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