Randomization in clinical trials with small sample sizes using group sequential designs.

Randomization in clinical trials with small sample sizes using group sequential designs.

Show other versions (1)

<h4>Background</h4>Group sequential designs, which allow early stopping for efficacy or futility, may benefit from balanced sample sizes at interim and final analyses. This requirement for balance limits the choice of admissible randomization procedures. We investigate if the choice of r...

Full description

Saved in:
Bibliographic Details
Main Authors: Daniel Bodden, Ralf-Dieter Hilgers, Franz König
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0325333
Tags: Add Tag
No Tags, Be the first to tag this record!
Show all versions (2)

Similar Items