The mTOR pathway is involved in the process of platelet-rich plasma improving intervertebral disc degeneration

The mTOR pathway is involved in the process of platelet-rich plasma improving intervertebral disc degeneration

Objective(s): Platelet-rich plasma (PRP) contains multiple growth hormones that may stimulate tissue repair. We aimed to assess PRP’s efficacy and explore possible mechanisms using the intervertebral disc degeneration (IDD) model. Materials and Methods: A total of 48 male Sprague-Dawley (SD) rats we...

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Bibliographic Details
Main Authors: Jing Luan, Qi Wang, Wei Zheng, Yongjin He
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-03-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
akt/mtor/p70s6k-signaling pathway
apoptosis
extracellular matrix- degradation
inflammatory factors intervertebral disc degeneration
oxidative stress
platelet-rich plasma
Online Access:https://ijbms.mums.ac.ir/article_25233_b6707a240a7962ae68e134e613620c50.pdf
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