Analysis of Cholera Epidemic Controlling Using Mathematical Modeling

The purpose of this study is to see whether it is possible to eradicate the disease theoretically using mathematical modeling with the aid of numerical simulation when disease occurs in a population by implementing adequate preventive measures. For this, we consider a mathematical model for the tran...

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Main Authors: Kinfe Hailemariam Hntsa, Berhe Nerea Kahsay
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:International Journal of Mathematics and Mathematical Sciences
Online Access:http://dx.doi.org/10.1155/2020/7369204
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author Kinfe Hailemariam Hntsa
Berhe Nerea Kahsay
author_facet Kinfe Hailemariam Hntsa
Berhe Nerea Kahsay
author_sort Kinfe Hailemariam Hntsa
collection DOAJ
description The purpose of this study is to see whether it is possible to eradicate the disease theoretically using mathematical modeling with the aid of numerical simulation when disease occurs in a population by implementing adequate preventive measures. For this, we consider a mathematical model for the transmission dynamics of cholera and its preventive measure as one cohort of individuals, namely, a protected cohort in addition to susceptible, infected, and recovered cohorts of individuals including the concentration of Vibrio cholerae in the contaminated aquatic reservoir with small modifications. We calculate the basic reproduction number, ℛ0, and investigate the existence and stability of equilibria. The model possessed forward bifurcation. Moreover, we compute the sensitivity indices of each parameter in relating to ℛ0 of the model. Numerical simulations are carried out to validate our theoretical results. The result indicates that the disease dies out in areas with adequate preventive measures and widespread and kills more people in areas with the inadequate preventive measures.
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institution Kabale University
issn 0161-1712
1687-0425
language English
publishDate 2020-01-01
publisher Wiley
record_format Article
series International Journal of Mathematics and Mathematical Sciences
spelling doaj-art-9b0b0d6c8ffa4f5a98b3590c98deb7392025-02-03T05:44:11ZengWileyInternational Journal of Mathematics and Mathematical Sciences0161-17121687-04252020-01-01202010.1155/2020/73692047369204Analysis of Cholera Epidemic Controlling Using Mathematical ModelingKinfe Hailemariam Hntsa0Berhe Nerea Kahsay1Department of Mathematics, Aksum University, Axum, EthiopiaDepartment of Mathematics, Aksum University, Axum, EthiopiaThe purpose of this study is to see whether it is possible to eradicate the disease theoretically using mathematical modeling with the aid of numerical simulation when disease occurs in a population by implementing adequate preventive measures. For this, we consider a mathematical model for the transmission dynamics of cholera and its preventive measure as one cohort of individuals, namely, a protected cohort in addition to susceptible, infected, and recovered cohorts of individuals including the concentration of Vibrio cholerae in the contaminated aquatic reservoir with small modifications. We calculate the basic reproduction number, ℛ0, and investigate the existence and stability of equilibria. The model possessed forward bifurcation. Moreover, we compute the sensitivity indices of each parameter in relating to ℛ0 of the model. Numerical simulations are carried out to validate our theoretical results. The result indicates that the disease dies out in areas with adequate preventive measures and widespread and kills more people in areas with the inadequate preventive measures.http://dx.doi.org/10.1155/2020/7369204
spellingShingle Kinfe Hailemariam Hntsa
Berhe Nerea Kahsay
Analysis of Cholera Epidemic Controlling Using Mathematical Modeling
International Journal of Mathematics and Mathematical Sciences
title Analysis of Cholera Epidemic Controlling Using Mathematical Modeling
title_full Analysis of Cholera Epidemic Controlling Using Mathematical Modeling
title_fullStr Analysis of Cholera Epidemic Controlling Using Mathematical Modeling
title_full_unstemmed Analysis of Cholera Epidemic Controlling Using Mathematical Modeling
title_short Analysis of Cholera Epidemic Controlling Using Mathematical Modeling
title_sort analysis of cholera epidemic controlling using mathematical modeling
url http://dx.doi.org/10.1155/2020/7369204
work_keys_str_mv AT kinfehailemariamhntsa analysisofcholeraepidemiccontrollingusingmathematicalmodeling
AT berhenereakahsay analysisofcholeraepidemiccontrollingusingmathematicalmodeling