Construction and Validation of a T Cell Exhaustion–Related Prognostic Signature in Cholangiocarcinoma

Conclusion: A prognostic signature was developed by four TEX-related genes, including PALLD, RAB31, ADAMTS2, and WISP1, which might be a powerful predictor for the prognosis of patients with CCA. These TEX-related genes were related to the infiltration of neutrophils, endothelial cells, B cells, and...

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Main Authors: Changshi Qian, Yuqiao Sun, Yihuai Yue
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:International Journal of Genomics
Online Access:http://dx.doi.org/10.1155/ijog/8823837
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author Changshi Qian
Yuqiao Sun
Yihuai Yue
author_facet Changshi Qian
Yuqiao Sun
Yihuai Yue
author_sort Changshi Qian
collection DOAJ
description Conclusion: A prognostic signature was developed by four TEX-related genes, including PALLD, RAB31, ADAMTS2, and WISP1, which might be a powerful predictor for the prognosis of patients with CCA. These TEX-related genes were related to the infiltration of neutrophils, endothelial cells, B cells, and T cells in CCA.
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language English
publishDate 2025-01-01
publisher Wiley
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series International Journal of Genomics
spelling doaj-art-9b0a92370584496d82eef6f2a8e97bed2025-08-20T03:09:08ZengWileyInternational Journal of Genomics2314-43782025-01-01202510.1155/ijog/8823837Construction and Validation of a T Cell Exhaustion–Related Prognostic Signature in CholangiocarcinomaChangshi Qian0Yuqiao Sun1Yihuai Yue2Department of Hepatopancreatobiliary SurgeryDepartment of Hepatopancreatobiliary SurgeryDepartment of SurgeryConclusion: A prognostic signature was developed by four TEX-related genes, including PALLD, RAB31, ADAMTS2, and WISP1, which might be a powerful predictor for the prognosis of patients with CCA. These TEX-related genes were related to the infiltration of neutrophils, endothelial cells, B cells, and T cells in CCA.http://dx.doi.org/10.1155/ijog/8823837
spellingShingle Changshi Qian
Yuqiao Sun
Yihuai Yue
Construction and Validation of a T Cell Exhaustion–Related Prognostic Signature in Cholangiocarcinoma
International Journal of Genomics
title Construction and Validation of a T Cell Exhaustion–Related Prognostic Signature in Cholangiocarcinoma
title_full Construction and Validation of a T Cell Exhaustion–Related Prognostic Signature in Cholangiocarcinoma
title_fullStr Construction and Validation of a T Cell Exhaustion–Related Prognostic Signature in Cholangiocarcinoma
title_full_unstemmed Construction and Validation of a T Cell Exhaustion–Related Prognostic Signature in Cholangiocarcinoma
title_short Construction and Validation of a T Cell Exhaustion–Related Prognostic Signature in Cholangiocarcinoma
title_sort construction and validation of a t cell exhaustion related prognostic signature in cholangiocarcinoma
url http://dx.doi.org/10.1155/ijog/8823837
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AT yuqiaosun constructionandvalidationofatcellexhaustionrelatedprognosticsignatureincholangiocarcinoma
AT yihuaiyue constructionandvalidationofatcellexhaustionrelatedprognosticsignatureincholangiocarcinoma