VIRTUAL SCREENING STRATEGY FOR IDENTIFYING NEW SMALL-MOLECULE ANTAGONISTS OF INTEGRIN αIIbβ3
Aim. To develop an optimal strategy for identifying new small-molecule antagonists of integrin αIIbβ3 using virtual screening. Methods. Molecular modeling. Results. The 7TMZ-based model demonstrated high classification accuracy (receiver operating characteristic area under the curve (ROC AUC):...
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| Format: | Article |
| Language: | English |
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National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry
2025-04-01
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| Series: | Biotechnologia Acta |
| Subjects: | |
| Online Access: | https://biotechnology.kiev.ua/images/BTA/2025/2_2025/Chuk2_2025%20.pdf |
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